EP 1784167 A2 20070516 - MULTI-LAYER TABLETS AND BIOADHESIVE DOSAGE FORMS
Title (en)
MULTI-LAYER TABLETS AND BIOADHESIVE DOSAGE FORMS
Title (de)
MEHRSCHICHTIGE TABLETTEN UND BIOADHÄSIVE DOSIERFORMEN
Title (fr)
COMPRIMES MULTICOUCHE ET FORMES POSOLOGIQUES BIOADHESIVES
Publication
Application
Priority
- US 2005030651 W 20050829
- US 60499104 P 20040827
- US 60499004 P 20040827
- US 60519804 P 20040827
- US 60519904 P 20040827
- US 60520004 P 20040827
- US 60520104 P 20040827
- US 60790504 P 20040908
- US 932704 A 20041209
- US 63581204 P 20041213
- US 65019105 P 20050204
- US 65037505 P 20050204
- US 2005007525 W 20050303
- US 67638305 P 20050429
Abstract (en)
[origin: WO2006031420A2] Bioadhesives coatings increase the gastrointestinal retention time of orally-ingested medicaments. Certain bioadhesive coatings producing a fracture strength of at least 100 N/m<SUP>2</SUP>, as measured on rat intestine, when applied to at least one surface of a pharmaceutical dosage form for oral delivery of a drug, result in a gastrointestinal retention time of at least 4 hours in a fed beagle dog model, during which the drug is released from the dosage form. Multi-layer tablets, particularly those including hydrophobic excipients, are useful in administering hygroscopic and/or deliquescent drugs. In addition, varying the amount of drug in multi-layer tablets allows the release rate of the drug to be controlled.
IPC 8 full level
CPC (source: EP)
A61K 9/2086 (2013.01); A61K 9/209 (2013.01); A61K 9/2027 (2013.01); A61K 9/2031 (2013.01); A61K 9/2054 (2013.01)
Citation (search report)
See references of WO 2006031420A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK YU
DOCDB simple family (publication)
WO 2006031420 A2 20060323; WO 2006031420 A3 20061130; AU 2005285298 A1 20060323; CA 2578845 A1 20060323; EP 1784167 A2 20070516
DOCDB simple family (application)
US 2005030651 W 20050829; AU 2005285298 A 20050829; CA 2578845 A 20050829; EP 05792519 A 20050829