EP 1787642 A1 20070523 - Compressed solid dosage form manufacturing process well-suited for use with drugs of low aqueous solubility and compressed solid dosage forms made thereby
Title (en)
Compressed solid dosage form manufacturing process well-suited for use with drugs of low aqueous solubility and compressed solid dosage forms made thereby
Title (de)
Herstellungsverfahren für komprimierte, feste Dosierungsformen, gut geeignet für Gebrauch bei Medikamenten mit niedriger Wasserlöslichkeit und dadurch hergestellte komprimierte, feste Dosierungsformen
Title (fr)
Procédé de fabrication d'une forme de dosage solide compressée appropriée à l'utilisation avec des médicaments ayant une solubilité aqueuse basse, et formes de dosage solide fabriquées à l'aide de celui-ci
Publication
Application
Priority
- EP 06026882 A 20041110
- EP 04810659 A 20041110
Abstract (en)
A pharmaceutical formulation of compounds with low aqueous solubility and method of manufacture thereof. The formulation may include a pharmacologically active compound having low aqueous solubility and starch in the amount of greater than about 25 weight percent. A manufacturing method may include blending the active compound and starch, compressing the blend into a solid, comminuting the solid into granules, wetting the granules, drying the granules, and tabletting the dried granules to make a solid pharmaceutical formulation.
IPC 8 full level
A61K 9/20 (2006.01)
CPC (source: EP)
A61K 9/1652 (2013.01); A61K 9/2059 (2013.01); A61K 9/2077 (2013.01)
Citation (search report)
- [X] WO 2004066910 A2 20040812 - GLENMARK PHARMACEUTICALS LTD [IN]
- [X] WO 0203987 A2 20020117 - AMERICAN HOME PROD [US]
- [X] EP 1438957 A1 20040721 - LILLY CO ELI [US]
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LU MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL HR LT LV MK YU
DOCDB simple family (publication)
DOCDB simple family (application)
EP 06026882 A 20041110; EP 09007193 A 20041110