EP 1794120 A4 20090826 - PEPTIDASE INHIBITORS
Title (en)
PEPTIDASE INHIBITORS
Title (de)
PEPTIDASEINHIBITOREN
Title (fr)
INHIBITEURS DE PEPTIDASE
Publication
Application
Priority
- US 2005025837 W 20050721
- US 59054104 P 20040723
- US 63436204 P 20041208
Abstract (en)
[origin: WO2006012395A2] The present invention relates to a series of novel compounds having the formula (I) wherein: X is NR<SUP>3</SUP> or O; n is 1 or 2; A is a bicyclic carbocycle and R1 and R1 are as described herein. The compounds are useful as DPP-IV inhibitors, such as for the treatment of diabetes.
IPC 8 full level
C07D 207/09 (2006.01); A61K 31/4025 (2006.01); A61P 35/00 (2006.01); C07D 207/10 (2006.01); C07D 403/12 (2006.01); C07D 413/12 (2006.01)
CPC (source: EP US)
A61P 3/10 (2017.12 - EP); A61P 5/50 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 207/10 (2013.01 - EP US); C07D 207/16 (2013.01 - EP US); C07D 277/04 (2013.01 - EP US); C07D 401/12 (2013.01 - EP US); C07D 403/12 (2013.01 - EP US); C07D 405/12 (2013.01 - EP US)
Citation (search report)
- [Y] WO 0034241 A1 20000615 - NOVARTIS AG [CH], et al
- [PX] WO 2005021536 A2 20050310 - SANOFI SYNTHELABO [FR], et al
- [Y] VILLHAUER E B ET AL: "1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine: A Potent, Selective, and Orally Bioavailable Dipeptidyl Peptidase IV Inhibitor with Antihyperglycemic Properties", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, US, vol. 46, no. 13, 1 January 2003 (2003-01-01), pages 2774 - 2789, XP002497964, ISSN: 0022-2623
- See references of WO 2006012395A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2006012395 A2 20060202; WO 2006012395 A3 20060504; AT E553077 T1 20120415; AU 2005267093 A1 20060202; AU 2005267093 B2 20091001; CA 2574418 A1 20060202; CN 101087756 A 20071212; CN 101087756 B 20110406; EP 1794120 A2 20070613; EP 1794120 A4 20090826; EP 1794120 B1 20120411; JP 2008507541 A 20080313; US 2008234292 A1 20080925; US 7842707 B2 20101130
DOCDB simple family (application)
US 2005025837 W 20050721; AT 05783778 T 20050721; AU 2005267093 A 20050721; CA 2574418 A 20050721; CN 200580031672 A 20050721; EP 05783778 A 20050721; JP 2007522735 A 20050721; US 57185705 A 20050721