EP 1797032 A1 20070620 - POLYMORPHS OF THE CYSTEINE PROTEASE INHIBITOR N-(1-CYANOCYCLOPROPYL)-3-CYCLOPROPYLMETHANESULFONYL-2(R)-[2,2,2-TRIFLUORO-1(S)-(4-FLUOROPHENYL)ETHYLAMINO]PROPIONAMIDE
Title (en)
POLYMORPHS OF THE CYSTEINE PROTEASE INHIBITOR N-(1-CYANOCYCLOPROPYL)-3-CYCLOPROPYLMETHANESULFONYL-2(R)-[2,2,2-TRIFLUORO-1(S)-(4-FLUOROPHENYL)ETHYLAMINO]PROPIONAMIDE
Title (de)
POLYMORPHE DES CYSTEINPROTEASEINHIBITORS N-(1-CYANOCYCLOPROPYL)-3-CYCLOPROPYLMETHANSULFONYL-2(R)-[2,2,2-TRIFLUOR-1(S)-(4-FLUORPHENYL)ETHYLAMINO]PROPIONAMID
Title (fr)
FORMES POLYMORPHES DU N-(1-CYANOCYCLOPROPYL)-3-CYCLOPROPYLMÉTHANESULFONYL-2(R)-(2,2,2-TRIFLUORO-1(S)-(4-FLUOROPHÉNYL)ÉTHYLAMINO)PROPIONAMIDE, UN INHIBITEUR DE LA CYSTÉINE PROTÉASE
Publication
Application
Priority
- US 2005033074 W 20050916
- US 2004030442 W 20040917
- US 94376804 A 20040917
- US 66424405 P 20050321
Abstract (en)
[origin: WO2006034006A1] The present invention is directed to polymorphs of N-(1-cyanocyclopropyl)-3-cyclopropylmethanesulfonyl-2(R)-(2,2,2-trifluoro-1(S)-4-fluorophenylethylamino)-propionamide, methods of using them to treat a disease mediated by cathepsin S, pharmaceutical compositions comprising such polymorphs, and processes for preparing them.
IPC 8 full level
C07C 317/48 (2006.01); A61K 31/277 (2006.01)
CPC (source: EP)
A61P 3/10 (2017.12); A61P 9/10 (2017.12); A61P 11/00 (2017.12); A61P 11/06 (2017.12); A61P 15/08 (2017.12); A61P 17/00 (2017.12); A61P 17/06 (2017.12); A61P 19/02 (2017.12); A61P 21/04 (2017.12); A61P 25/00 (2017.12); A61P 25/04 (2017.12); A61P 25/28 (2017.12); A61P 29/00 (2017.12); A61P 35/00 (2017.12); A61P 37/06 (2017.12); A61P 37/08 (2017.12); A61P 43/00 (2017.12); C07C 317/48 (2013.01); C07C 2601/02 (2017.04)
Citation (search report)
See references of WO 2006034006A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2006034006 A1 20060330; AU 2005287048 A1 20060330; CA 2580219 A1 20060330; EP 1797032 A1 20070620; JP 2008513473 A 20080501
DOCDB simple family (application)
US 2005033074 W 20050916; AU 2005287048 A 20050916; CA 2580219 A 20050916; EP 05798153 A 20050916; JP 2007532482 A 20050916