EP 1804786 A4 20080102 - SUBSTITUTED N-ARYL-9-OXO-9H-FLUORENE-1-CARBOXAMIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS

Title (en)

SUBSTITUTED N-ARYL-9-OXO-9H-FLUORENE-1-CARBOXAMIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS

SUBSTITUIERTE N-ARYL-9-OXO-9H-FLUORENE-1-CARBOXAMIDE UND ANALOGA ALS AKTIVATOREN VON CASPASEN UND APOPTOSE-AUSLÖSERN

N-ARYL-9-OXO-9H-FLUORENE-1-CARBOXAMIDES SUBSTITUES ET ANALOGUES UTILISES COMME ACTIVATEURS DES CASPASES ET INDUCTEURS DE L'APOPTOSE

[origin: WO2006039356A2] The present invention is directed to substituted <i

A61K 31/165 (2006.01); A61K 31/343 (2006.01); A61K 31/381 (2006.01); A61K 31/403 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); C07D 209/82 (2006.01); C07D 209/88 (2006.01)

A61K 31/165 (2013.01 - EP US); A61K 31/167 (2013.01 - EP US); A61K 31/343 (2013.01 - EP US); A61K 31/381 (2013.01 - EP US); A61K 31/403 (2013.01 - EP US); A61P 29/00 (2017.12 - EP); A61P 35/00 (2017.12 - EP); C07D 209/88 (2013.01 - EP US)

[X] EP 1233013 A1 20020821 - AJINOMOTO KK [JP]
[X] EP 0136284 A2 19850403 - HUTTER & SCHRANTZ SIEBTECHNIK [AT]
[E] WO 2006010082 A1 20060126 - ARQULE INC [US], et al
[E] WO 2005105777 A1 20051110 - PHARMACIA & UPJOHN CO LLC [US], et al
[X] EP 0945450 A1 19990929 - SHIONOGI & CO [JP]
[X] EP 1264820 A1 20021211 - FUJISAWA PHARMACEUTICAL CO [JP]
[X] PALMER P D ET AL: "Potential antitumor agents. 54. Chromophore requirements for in vivo antitumor activity among the general class of linear tricyclic carboxamides", JOURNAL OF MEDICINAL CHEMISTRY, vol. 31, 1988, pages 707 - 712, XP002458417
See references of WO 2006039356A2

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

US 2005034890 W 20050929; EP 05802540 A 20050929; US 66406005 A 20050929