EP 1804795 A4 20071107 - ENANTIOMERIC COMPOSITIONS OF CICLETANINE, ALONE AND IN COMBINATION WITH OTHER AGENTS, FOR THE TREATMENT OF DISEASE
Title (en)
ENANTIOMERIC COMPOSITIONS OF CICLETANINE, ALONE AND IN COMBINATION WITH OTHER AGENTS, FOR THE TREATMENT OF DISEASE
Title (de)
ENANTIOMERE ZUSAMMENSETZUNGEN VON CICLETANIN, ALLEIN ODER IN KOMBINATION MIT ANDEREN MITTELN, ZUR BEHANDLUNG VON KRANKHEITEN
Title (fr)
COMPOSITIONS ENANTIOMERES DE CICLETANINE, SEULES OU COMBINEES A D'AUTRES AGENTS, UTILISEES A DES FINS THERAPEUTIQUES
Publication
Application
Priority
- US 2005034763 W 20050922
- US 61236904 P 20040922
- US 61232304 P 20040922
- US 3530805 A 20050113
- US 3532805 A 20050113
- US 3523105 A 20050113
- US 68468405 P 20050526
- US 23272405 A 20050921
Abstract (en)
[origin: WO2006034510A2] Preferred embodiments of the present invention are related to novel therapeutic drugs and drug combinations, and associated methods, for treating and/or preventing complications in patients with diabetes, metabolic syndrome, and/or hypertension. More particularly, aspects of the present invention are related to the use of cicletanine as a monotherapy or in combination with other agents for treatment of disease. Cicletanine, as either a monotherapy or in combination with other drugs, may have the form of a non-racemic mixture of the negative (-) and positive (+) enantiomers of cicletanine, or as either the (-) or (+) enantiomer alone.
IPC 8 full level
A61K 31/4355 (2006.01); A01N 25/00 (2006.01); A61P 3/00 (2006.01); A61P 9/12 (2006.01)
CPC (source: EP)
A61K 31/4355 (2013.01); A61K 31/4741 (2013.01); A61P 3/00 (2017.12); A61P 9/12 (2017.12)
Citation (search report)
- [PY] WO 2005009446 A1 20050203 - COTHERIX INC [US], et al
- [PY] WO 2004091612 A1 20041028 - SYNOSENS KUTATO ES FEJLESZT & [HU], et al
- [PY] WO 2005021039 A1 20050310 - COTHERIX INC [US], et al
- [Y] KOHZUKI, M. ET AL.: "Renal-protective effect of nondepressor dose of cicletanine in diabetic rats with hypertension", AMERICAN JOURNAL OF HYPERTENSION, vol. 13, 2000, pages 298 - 306, XP002452885
- [Y] BUCHHOLZ, R.A. ET AL.: "Natriuretic and diuretic effects of cicletanine in conscious, hydrated, normotensive rats", DRUG DEVELOPMENT RESEARCH, vol. 25, 1992, pages 125 - 137, XP002452886
- [Y] PASSA, P.: "Etude de la tolérance du ciclétanine chez des patients hypertendus présentant des troubles métaboliques", ARCH MAL COEUR, vol. 824, 1989, pages 135 - 138, XP009090138
- See references of WO 2006034510A2
Citation (examination)
US 5661147 A 19970826 - MACHII DAISUKE [JP], et al
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2006034510 A2 20060330; WO 2006034510 A3 20060601; CA 2581337 A1 20060330; EP 1804795 A2 20070711; EP 1804795 A4 20071107
DOCDB simple family (application)
US 2005034763 W 20050922; CA 2581337 A 20050922; EP 05800096 A 20050922