EP 1807123 A2 20070718 - A METHOD FOR IMPROVEMENT OF TOLERANCE FOR THERAPEUTICALLY EFFECTIVE AGENTS DELIVERED BY INHALATION
Title (en)
A METHOD FOR IMPROVEMENT OF TOLERANCE FOR THERAPEUTICALLY EFFECTIVE AGENTS DELIVERED BY INHALATION
Title (de)
VERFAHREN ZUR VERBESSERUNG DER TOLERANZ GEBENÜBER THERAPEUTISCH WIRKSAMEN MITTELN, DIE DURCH INHALATION ABGEGEBEN WERDEN
Title (fr)
PROCEDE PERMETTANT D'AMELIORER LA TOLERANCE A DES AGENTS EFFICACES SUR LE PLAN THERAPEUTIQUE ADMINISTRES PAR INHALATION
Publication
Application
Priority
- US 2005003532 W 20050128
- US 61165604 P 20040920
- US 2004036926 W 20041104
- US 63502204 P 20041209
Abstract (en)
[origin: WO2006060027A2] A method for improvement of tolerance for therapeutically effective agents delivered by inhalation comprising a pretreatment of a patient with a nebulized lidocaine or a lidocaine-like compound administered immediately or up to about thirty minutes before administration of the primary therapeutically effective agent. The pretreatment of the patient with the nebulized lidocaine or a lidocaine-like compound improves airway tolerance and deposition of the agent in the lungs and makes such deposition more safe, efficacious, controllable and predictable. The method of the invention is especially useful for enhancement of deposition of immunosuppressive agents in the lung(s) of transplant patients, improved tolerance of the drugs by reducing cough, and improving pulmonary drug deposition.
IPC 8 full level
A61K 9/12 (2006.01); A61K 9/14 (2006.01); A61K 31/24 (2006.01); A61K 31/47 (2006.01)
CPC (source: EP)
A61K 9/0075 (2013.01); A61K 9/0078 (2013.01)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR LV MK YU
DOCDB simple family (publication)
WO 2006060027 A2 20060608; WO 2006060027 A3 20071213; AU 2005310312 A1 20060608; CA 2581053 A1 20060608; EP 1807123 A2 20070718; EP 1807123 A4 20100113
DOCDB simple family (application)
US 2005003532 W 20050128; AU 2005310312 A 20050128; CA 2581053 A 20050128; EP 05790821 A 20050128