EP 1809334 A2 20070725 - CONJUGATES WITH ENHANCED CELL UPTAKE ACTIVITY
Title (en)
CONJUGATES WITH ENHANCED CELL UPTAKE ACTIVITY
Title (de)
KONJUGATE MIT VERBESSERTER ZELLAUFNAHMEAKTIVITÄT
Title (fr)
CONJUGUÉ AYANT UNE ABSORPTION CELLULAIRE AMÉLIORÉE
Publication
Application
Priority
- EP 2005011991 W 20051109
- EP 04026934 A 20041112
- EP 05811041 A 20051109
Abstract (en)
[origin: EP1656951A1] This invention relates to a conjugate molecule comprising at least one first portion (I) comprising a carrier sequence and at least one second portion (II) comprising at lest one anti-tumot drug molecule or a protease inhibitor molecule, said conjugate molecule comprising D-enantiomeric amino acids in its portion (I). Furthermore, the invention relates to pharmaceutical compositions containing said conjugate molecule as well as to the use of said conjugate molecule for therapeutical treatment. Methods for improving cell permeability are disclosed as well.
IPC 8 full level
A61K 47/48 (2006.01); A61P 31/18 (2006.01); A61P 35/00 (2006.01); C07K 7/06 (2006.01)
CPC (source: EP)
A61K 47/645 (2017.07); A61P 31/00 (2017.12); A61P 31/04 (2017.12); A61P 31/12 (2017.12); A61P 31/18 (2017.12); A61P 35/00 (2017.12); A61P 43/00 (2017.12); C07K 5/1019 (2013.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01)
Citation (search report)
See references of WO 2006050930A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK YU
DOCDB simple family (publication)
EP 1656951 A1 20060517; AR 051765 A1 20070207; AU 2005303949 A1 20060518; BR PI0517843 A 20081021; CA 2585421 A1 20060518; CN 101072589 A 20071114; EA 200700976 A1 20071228; EP 1809334 A2 20070725; IL 182760 A0 20070724; JP 2008519785 A 20080612; WO 2006050930 A2 20060518; WO 2006050930 A3 20070426
DOCDB simple family (application)
EP 04026934 A 20041112; AR P050104743 A 20051111; AU 2005303949 A 20051109; BR PI0517843 A 20051109; CA 2585421 A 20051109; CN 200580038728 A 20051109; EA 200700976 A 20051109; EP 05811041 A 20051109; EP 2005011991 W 20051109; IL 18276007 A 20070423; JP 2007540568 A 20051109