Global Patent Index - EP 1814584 A2

EP 1814584 A2 20070808 - LIGANDS THAT ENHANCE ENDOGENOUS COMPOUNDS

Title (en)

LIGANDS THAT ENHANCE ENDOGENOUS COMPOUNDS

Title (de)

LIGANDEN ZUR VERBESSERUNG VON ENDOGENEN VERBINDUNGEN

Title (fr)

LIGANDS AMELIORANT DES COMPOSANTS ENDOGENES

Publication

EP 1814584 A2 20070808 (EN)

Application

EP 05801585 A 20051110

Priority

  • GB 2005004319 W 20051110
  • US 98584704 A 20041110

Abstract (en)

[origin: WO2006051288A2] The invention relates to ligands that comprise a moiety (e.g., a dAb) that has a binding site with binding specificity for an endogenous target compound but do not substantially inhibit the activity of said endogenous target compound. Preferably, the ligand does not bind to the active site of an endogenous target compound. The invention relates to the use of such a ligand for the manufacture of a medicament for increasing the half-life, bioavailability, activity or amount of an endogenous target compound to which the ligand binds.

IPC 8 full level

A61K 39/395 (2006.01)

CPC (source: EP KR)

A61K 39/395 (2013.01 - KR); A61P 1/00 (2017.12 - EP); A61P 9/00 (2017.12 - EP); A61P 11/00 (2017.12 - EP); A61P 11/06 (2017.12 - EP); A61P 19/02 (2017.12 - EP); A61P 25/28 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 31/04 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 37/00 (2017.12 - EP); A61P 37/02 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07K 16/24 (2013.01 - EP); C07K 16/26 (2013.01 - EP); C07K 16/28 (2013.01 - KR); A61K 2039/505 (2013.01 - EP); C07K 2317/21 (2013.01 - EP); C07K 2317/31 (2013.01 - EP); C07K 2317/569 (2013.01 - EP)

Citation (search report)

See references of WO 2006051288A2

Citation (examination)

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

Designated extension state (EPC)

HR

DOCDB simple family (publication)

WO 2006051288 A2 20060518; WO 2006051288 A3 20060817; AU 2005303584 A1 20060518; BR PI0517569 A 20081014; CA 2587206 A1 20060518; CN 101098712 A 20080102; CN 101724071 A 20100609; EP 1814584 A2 20070808; EP 2420251 A2 20120222; EP 2420251 A3 20130313; JP 2008519813 A 20080612; KR 20070084069 A 20070824; KR 20070089930 A 20070904; MA 29221 B1 20080201; MA 29427 B1 20080502; NO 20071788 L 20070706; NO 20072475 L 20070806; RU 2007112509 A 20081127; RU 2007117196 A 20081220; RU 2401842 C2 20101020

DOCDB simple family (application)

GB 2005004319 W 20051110; AU 2005303584 A 20051110; BR PI0517569 A 20051110; CA 2587206 A 20051110; CN 200580046184 A 20051110; CN 200910246166 A 20051007; EP 05801585 A 20051110; EP 11161978 A 20051110; JP 2007540709 A 20051110; KR 20077010453 A 20070508; KR 20077012946 A 20070608; MA 29876 A 20070507; MA 29969 A 20070606; NO 20071788 A 20070403; NO 20072475 A 20070516; RU 2007112509 A 20051007; RU 2007117196 A 20051110