EP 1815022 A2 20070808 - METHOD OF DETERMINING A CELLULAR RESPONSE TO A BIOLOGICAL AGENT
Title (en)
METHOD OF DETERMINING A CELLULAR RESPONSE TO A BIOLOGICAL AGENT
Title (de)
VERFAHREN ZUR BESTIMMUNG DER ZELLREAKTION AUF EINEN BIOLOGISCHEN WIRKSTOFF
Title (fr)
MÉTHODE DE DÉTERMINATION D'UNE RÉPONSE CELLULAIRE À UN AGENT BIOLOGIQUE
Publication
Application
Priority
- US 2005042407 W 20051121
- US 63032004 P 20041122
- US 67816505 P 20050504
- US 28348105 A 20051118
- US 28348205 A 20051118
- US 28348305 A 20051118
- US 28348405 A 20051118
Abstract (en)
[origin: CA2587786A1] A reverse transfection apparatus can be used for introducing siRNA into a ce ll to effect gene silencing. Such an apparatus can include a well plate having a well configured for transfecting cells. The well can include a substantially dry gene silencing composition that has at least a first siRNA which silence s a first target gene. The gene silencing composition can be configured such that the at least first siRNA is capable of being solubilized or suspended i n an aqueous medium in an amount sufficient for transfecting cells in the well . Additionally, the at least first siRNA can include a modification or a conjugate. The reverse transfection apparatus can be provided as a kit or system that additionally includes cells, polynucleotide carriers, reverse transfection reagents, and the like.
IPC 8 full level
C07H 19/00 (2006.01); A61K 31/70 (2006.01); C12N 15/11 (2006.01); C12N 15/87 (2006.01); C12Q 1/68 (2006.01); G01N 33/50 (2006.01)
CPC (source: EP KR)
C12M 1/00 (2013.01 - KR); C12M 1/18 (2013.01 - KR); C12M 1/26 (2013.01 - KR); C12Q 1/6809 (2013.01 - EP); G01N 33/502 (2013.01 - EP)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
AT E519772 T1 20110815; AU 2005322468 A1 20060706; AU 2005322468 A2 20060706; AU 2005322468 B2 20110310; CA 2587786 A1 20060706; CA 2587786 C 20171205; CN 101107352 A 20080116; CN 101107352 B 20130320; EP 1814895 A2 20070808; EP 1814895 A4 20080528; EP 1814895 B1 20110810; EP 1814994 A2 20070808; EP 1814994 A4 20100714; EP 1815022 A2 20070808; EP 1815022 A4 20090325; JP 2008532480 A 20080821; KR 101277646 B1 20130625; KR 20070118585 A 20071217
DOCDB simple family (application)
AT 05852038 T 20051121; AU 2005322468 A 20051121; CA 2587786 A 20051121; CN 200580047054 A 20051121; EP 05849672 A 20051121; EP 05852038 A 20051121; EP 05857003 A 20051121; JP 2007543423 A 20051121; KR 20077013989 A 20051121