EP 1819320 B1 20081001 - ORALLY DISPERSIBLE PHARMACEUTICAL COMPOSITION AND PROCESS FOR THE PREPARATION THEREOF
Title (en)
ORALLY DISPERSIBLE PHARMACEUTICAL COMPOSITION AND PROCESS FOR THE PREPARATION THEREOF
Title (de)
ORAL DISPERGIERBARE PHARMAZEUTISCHE ZUSAMMENSETZUNG UND VERFAHREN ZU IHRER HERSTELLUNG
Title (fr)
COMPOSITION PHARMACEUTIQUE ORODISPERSIBLE ET PROCEDE DE PREPARATION DE CELLE-CI
Publication
Application
Priority
- EP 2005012859 W 20051125
- IT MI20042356 A 20041210
Abstract (en)
[origin: WO2006061142A1] A process for preparing an orally dispersible solid pharmaceutical form comprises the following steps: a) coating the active ingredient with at least one hydrophilic carboxylate polymer, b) granulating the coated active ingredient obtained in step (a) with at least one lipid compound having a melting point lower than that of the active ingredient, c) mixing the granulate obtained in step (b) with at least one hydrophilic natural polymer having high molecular weight, and d) mixing the granulate obtained in step (c) with ingredients suitable for obtaining an orally dispersible solid pharmaceutical form. An orally dispersible solid pharmaceutical form comprises an active ingredient coated with at least one hydrophilic carboxylate polymer and at least one lipid compound, in which the said coated active ingredient is embedded in a matrix comprising at least one hydrophilic natural polymer having high molecular weight.
IPC 8 full level
A61K 9/20 (2006.01)
CPC (source: EP KR US)
A61K 9/0056 (2013.01 - EP US); A61K 9/20 (2013.01 - KR); A61K 9/2081 (2013.01 - EP US); A61K 9/28 (2013.01 - KR); A61K 31/185 (2013.01 - KR); A61P 29/00 (2017.12 - EP); A61K 9/5078 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2006061142 A1 20060615; AR 052149 A1 20070307; AT E409463 T1 20081015; AU 2005313588 A1 20060615; AU 2005313588 B2 20120524; BR PI0518847 A2 20081209; CA 2585940 A1 20060615; CA 2585940 C 20120925; CN 101065113 A 20071031; CN 101065113 B 20120411; DE 602005010115 D1 20081113; DK 1819320 T3 20090112; EA 010587 B1 20081030; EA 200700877 A1 20071026; EP 1819320 A1 20070822; EP 1819320 B1 20081001; ES 2314742 T3 20090316; GE P20094589 B 20090112; HK 1105872 A1 20080229; IL 182865 A0 20070819; IL 182865 A 20100630; IT MI20042356 A1 20050310; JP 2008522995 A 20080703; JP 4980926 B2 20120718; KR 101249855 B1 20130405; KR 20070085941 A 20070827; MX 2007006705 A 20071008; PL 1819320 T3 20090331; PT 1819320 E 20081120; SI 1819320 T1 20090228; UA 89656 C2 20100225; US 2009074867 A1 20090319
DOCDB simple family (application)
EP 2005012859 W 20051125; AR P050105143 A 20051209; AT 05817592 T 20051125; AU 2005313588 A 20051125; BR PI0518847 A 20051125; CA 2585940 A 20051125; CN 200580040370 A 20051125; DE 602005010115 T 20051125; DK 05817592 T 20051125; EA 200700877 A 20051125; EP 05817592 A 20051125; ES 05817592 T 20051125; GE AP2005010172 A 20051125; HK 07111295 A 20071018; IL 18286507 A 20070430; IT MI20042356 A 20041210; JP 2007544783 A 20051125; KR 20077012985 A 20051125; MX 2007006705 A 20051125; PL 05817592 T 20051125; PT 05817592 T 20051125; SI 200530528 T 20051125; UA A200707792 A 20051125; US 57776205 A 20051125