EP 1819373 A2 20070822 - COATINGS WITH CRYSTALLIZED ACTIVE AGENT(S)
Title (en)
COATINGS WITH CRYSTALLIZED ACTIVE AGENT(S)
Title (de)
BESCHICHTUNGEN MIT KRISTALLISIERTEN WIRKSTOFFEN
Title (fr)
REVETEMENTS COMPRENANT UN OU PLUSIEURS AGENTS ACTIFS CRISTALLISES
Publication
Application
Priority
- US 2005044198 W 20051206
- US 63407004 P 20041207
Abstract (en)
[origin: WO2006063021A2] The present invention relates to coatings with crystallized active agent(s) and related methods. In an embodiment, the invention includes a method for coating a medical device including selecting a solvent and a polymer, selecting a concentration of an active agent of at least a certain amount of saturation, forming a coating composition having the selected concentration of the active agent, and applying the coating composition to the medical device. In an embodiment, the invention includes an elution control coating disposed on a medical device, the elution control coating including a polymer, and an active agent, wherein the active agent is at least about 80% crystallized within one week of being disposed on the medical device. In an embodiment, the invention includes a method for enhancing the formation of active agent crystals within a coating layer including forming a coating solution and adjusting the concentration of the active agent in the coating solution to reach some percentage of the active agent saturation point. In an embodiment, the invention includes a method of enhancing crystallization of an active agent, the method including forming a coating solution comprising a polymer, an active agent, and a solvent; applying the coating solution to a substrate; and increasing the rate of active agent nucleation within the coating.
IPC 8 full level
A61L 27/34 (2006.01); A61L 27/50 (2006.01); A61L 27/54 (2006.01); A61L 31/10 (2006.01); A61L 31/14 (2006.01); A61L 31/16 (2006.01)
CPC (source: EP US)
A61K 6/20 (2020.01 - EP US); A61K 31/56 (2013.01 - EP US); A61L 27/34 (2013.01 - EP US); A61L 27/50 (2013.01 - EP US); A61L 27/54 (2013.01 - EP US); A61L 31/10 (2013.01 - EP US); A61L 31/14 (2013.01 - EP US); A61L 31/16 (2013.01 - EP US); A61L 2300/216 (2013.01 - US); A61L 2300/222 (2013.01 - EP US); A61L 2300/43 (2013.01 - EP US); A61L 2300/602 (2013.01 - US); A61L 2300/606 (2013.01 - EP US); A61L 2300/63 (2013.01 - EP US); A61L 2420/02 (2013.01 - EP US); A61L 2420/06 (2013.01 - US)
Citation (search report)
See references of WO 2006063021A2
Designated contracting state (EPC)
DE FR GB IE IT
DOCDB simple family (publication)
WO 2006063021 A2 20060615; WO 2006063021 A3 20061012; CA 2589761 A1 20060615; EP 1819373 A2 20070822; US 2006134168 A1 20060622; US 2010093686 A1 20100415; US 2015374886 A1 20151231; US 2017007745 A1 20170112; US 9427501 B2 20160830; US 9649413 B2 20170516; US 9795720 B2 20171024
DOCDB simple family (application)
US 2005044198 W 20051206; CA 2589761 A 20051206; EP 05853187 A 20051206; US 201514753186 A 20150629; US 201615211833 A 20160715; US 29516705 A 20051206; US 63616409 A 20091211