EP 1824457 B1 20160217 - MULTIPARTICULATE FORM OF ADMINISTRATION, COMPRISING NUCLEIC ACID-CONTAINING MUCOADHESIVE ACTIVE INGREDIENTS, AND METHOD FOR PRODUCING SAID FORM OF ADMINISTRATION
Title (en)
MULTIPARTICULATE FORM OF ADMINISTRATION, COMPRISING NUCLEIC ACID-CONTAINING MUCOADHESIVE ACTIVE INGREDIENTS, AND METHOD FOR PRODUCING SAID FORM OF ADMINISTRATION
Title (de)
MULTIPARTIKULÄRE ARZNEIFORM, ENTHALTEND MUCOADHAESIV FORMULIERTE NUKLEINSÄURE-WIRKSTOFFE, SOWIE EIN VERFAHREN ZUR HERSTELLUNG DER ARZNEIFORM
Title (fr)
FORME GALENIQUE MULTIPARTICULAIRE RENFERMANT DES PRINCIPES ACTIFS CONTENANT UN ACIDE NUCLEIQUE A FORMULATION MUCOADHESIVE, AINSI QUE PROCEDE POUR PRODUIRE CETTE FORME GALENIQUE
Publication
Application
Priority
- EP 2005011864 W 20051105
- DE 102004059792 A 20041210
Abstract (en)
[origin: US2009280183A1] The invention relates to an oral, multiparticulate form of administration, comprising pellets in the size ranging from 50 to 2500 $g(m)m which are substantially constituted of a) an inner matrix layer containing nanoparticles that contain a nucleic acid active ingredient and being embedded in a matrix of a polymer having a mucoadhesive effect, and b) an outer film coating, substantially consisting of an anionic polymer or copolymer that is optionally formulated with pharmaceutically conventional adjuvants, especially emollients.
IPC 8 full level
A61K 9/16 (2006.01); A61K 31/7088 (2006.01)
CPC (source: EP KR US)
A61K 9/1676 (2013.01 - EP US); A61K 9/1694 (2013.01 - EP US); A61K 9/209 (2013.01 - KR); A61K 9/28 (2013.01 - KR); A61K 9/5138 (2013.01 - EP US); A61K 9/5192 (2013.01 - EP US); A61K 31/7088 (2013.01 - EP KR US); A61P 1/00 (2017.12 - EP); A61K 9/1652 (2013.01 - EP US); B82Y 5/00 (2013.01 - KR)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
US 2009280183 A1 20091112; US 8568778 B2 20131029; BR PI0515815 A 20080805; BR PI0515815 B1 20190205; BR PI0515815 B8 20210525; CA 2586597 A1 20060615; CA 2586597 C 20130910; CN 101060835 A 20071024; CN 101060835 B 20130102; DE 102004059792 A1 20060614; EP 1824457 A1 20070829; EP 1824457 B1 20160217; ES 2569354 T3 20160510; HK 1110205 A1 20080711; HU E028793 T2 20170130; IL 183753 A0 20070920; IL 183753 A 20161229; JP 2008522989 A 20080703; JP 5578764 B2 20140827; KR 101319773 B1 20131017; KR 20070085894 A 20070827; MX 2007006343 A 20070704; PL 1824457 T3 20160729; SI 1824457 T1 20160630; TW 200635617 A 20061016; WO 2006061069 A1 20060615
DOCDB simple family (application)
US 72139905 A 20051105; BR PI0515815 A 20051105; CA 2586597 A 20051105; CN 200580037293 A 20051105; DE 102004059792 A 20041210; EP 05807707 A 20051105; EP 2005011864 W 20051105; ES 05807707 T 20051105; HK 08100739 A 20080121; HU E05807707 A 20051105; IL 18375307 A 20070607; JP 2007544750 A 20051105; KR 20077012902 A 20051105; MX 2007006343 A 20051105; PL 05807707 T 20051105; SI 200532058 A 20051105; TW 94140339 A 20051116