EP 1836313 A2 20070926 - METHODS FOR ASSESSING PATIENTS WITH ACUTE MYELOID LEUKEMIA
Title (en)
METHODS FOR ASSESSING PATIENTS WITH ACUTE MYELOID LEUKEMIA
Title (de)
VERFAHREN ZUR BEURTEILUNG VON PATIENTEN MIT AKUTER MYELOIDER LEUKÄMIE
Title (fr)
PROCEDE D'ESTIMATION DE PATIENTS SOUFFRANT D'UNE LEUCEMIE MYELOIDE AIGUE
Publication
Application
Priority
- US 2005046100 W 20051219
- US 63726504 P 20041217
- US 67011605 P 20050411
- US 74118005 P 20051201
Abstract (en)
[origin: WO2006066240A2] Methods for treating cancer, and preferably hematological malignancy, patients include analyzing gene expression profiles and/or molecular markers of a patient to determine status and/or prognosis of the patient. The invention also provides methods of analyzing whether a non-relapsed or non-refractory patient is likely to respond to treatment with farnesyl transferase inhibitors (FTIs) and, optionally, other therapeutics. The methods are also useful for monitoring patient therapy and for selecting a course of therapy. Genes modulated in response to FTI treatment are provided and are used in formulating the profiles.
IPC 8 full level
C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12P 19/34 (2006.01); C12Q 1/68 (2006.01)
CPC (source: EP KR)
C12Q 1/6809 (2013.01 - EP KR); C12Q 1/6837 (2013.01 - KR); C12Q 1/6886 (2013.01 - EP KR); C12Q 2565/501 (2013.01 - KR); C12Q 2600/106 (2013.01 - EP KR); C12Q 2600/154 (2013.01 - EP KR); C12Q 2600/158 (2013.01 - EP KR)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK YU
DOCDB simple family (publication)
WO 2006066240 A2 20060622; WO 2006066240 A3 20080717; WO 2006066240 A8 20060908; AU 2005316291 A1 20060622; BR PI0515794 A 20080805; CA 2589055 A1 20060622; EP 1836313 A2 20070926; EP 1836313 A4 20100630; IL 183555 A0 20070920; JP 2008523822 A 20080710; KR 20070099564 A 20071009; MX 2007007401 A 20071008
DOCDB simple family (application)
US 2005046100 W 20051219; AU 2005316291 A 20051219; BR PI0515794 A 20051219; CA 2589055 A 20051219; EP 05854761 A 20051219; IL 18355507 A 20070530; JP 2007547020 A 20051219; KR 20077013783 A 20070618; MX 2007007401 A 20051219