EP 1838339 A2 20071003 - AGER-PEPTIDES AND USE THEREOF
Title (en)
AGER-PEPTIDES AND USE THEREOF
Title (de)
AGER-PEPTIDE UND DEREN VERWENDUNG
Title (fr)
PEPTIDES DE PTAG ET LEUR UTILISATION
Publication
Application
Priority
- EP 2006000420 W 20060118
- DE 102005002353 A 20050118
- US 64521105 P 20050118
- US 66870405 P 20050405
- DE 102005015832 A 20050406
- US 68121105 P 20050513
- DE 102005022285 A 20050513
Abstract (en)
[origin: WO2006077101A2] The invention relates to the identification, functionality and use of domains of the N-terminus of the receptor for Advanced Glycation End Products (AGER). Said domains are highly conserved in all AGER protein sequences, with the designated receptor multimerisation epitop (RME). They represent mediators for the AGER automatic association and heteromerisation with other proteins. The invention also relates to the identification, functionality and use of peptides which are derived from the C-domains of AGER (AGER-CDP). The inventive AGER-RMEs and AGER-CDPs are suitable as targets for identifying AGER-ligands, which modulate natural ligand exchange effects as immunogens for the active or passive immunisation of individuals, as diagnostic means which are used to identify immunogenic reactions, and as peptide ligands which are used to modulate protein-protein-exchange effects involving AGER.
IPC 8 full level
A61K 39/00 (2006.01); C07K 14/47 (2006.01); C07K 16/00 (2006.01)
CPC (source: EP)
A61P 1/00 (2017.12); A61P 3/00 (2017.12); A61P 3/10 (2017.12); A61P 9/08 (2017.12); A61P 9/10 (2017.12); A61P 13/12 (2017.12); A61P 17/00 (2017.12); A61P 17/02 (2017.12); A61P 17/06 (2017.12); A61P 19/02 (2017.12); A61P 25/00 (2017.12); A61P 25/02 (2017.12); A61P 25/28 (2017.12); A61P 27/02 (2017.12); A61P 29/00 (2017.12); A61P 31/12 (2017.12); A61P 35/00 (2017.12); A61P 37/02 (2017.12); C07K 14/4748 (2013.01); C07K 14/705 (2013.01)
Citation (search report)
See references of WO 2006077101A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
HR
DOCDB simple family (publication)
WO 2006077101 A2 20060727; WO 2006077101 A3 20060928; EP 1838339 A2 20071003; JP 2008526243 A 20080724
DOCDB simple family (application)
EP 2006000420 W 20060118; EP 06706286 A 20060118; JP 2007550773 A 20060118