Global Patent Index - EP 1838666 A1

EP 1838666 A1 2007-10-03 - PROCESS FOR PREPARATION OF A PHARMACEUTICAL GRADE CALCIPOTRIOL ANHYDROUS

Title (en)

PROCESS FOR PREPARATION OF A PHARMACEUTICAL GRADE CALCIPOTRIOL ANHYDROUS

Title (de)

VERFAHREN ZUR HERSTELLUNG VON WASSERFREIEM CALCIPOTRIOL PHARMAZEUTISCHER QUALITÄT

Title (fr)

PROCEDE POUR LA PREPARATION D'UN CALCIPOTRIOL ANHYDRE DE QUALITE PHARMACEUTIQUE

Publication

EP 1838666 A1 (EN)

Application

EP 05821873 A

Priority

  • PL 2005000087 W
  • PL 37201304 A

Abstract (en)

[origin: WO2006071129A1] A process for the preparation of a pharmaceutical grade calcipotriol anhydrous, wherein a crude calcipotriol is dissolved in one or more solvents, of which at least one forms azeotropic system with water, and then: a) in the case the water and impurities content in the substance exceeds the admissible level, solvents are azeotropically evaporated under reduced pressure, resulting in a clear anhydrous oil , or (b) in the case the water content in the substance does not exceed the admissible level, the solution is allowed to crystallize the product, (c) product obtained in step (a) or (b) is crystallized at least once from anhydrous solvent or mixture of anhydrous solvents.

IPC 8 full level (invention and additional information)

C07C 401/00 (2006.01)

CPC (invention and additional information)

C07C 401/00 (2013.01)

Citation (third parties)

Third party :

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

EPO simple patent family

WO 2006071129 A1 20060706; WO 2006071129 B1 20060831; EP 1838666 A1 20071003; PL 207034 B1 20101029; PL 372013 A1 20060710; US 2008214876 A1 20080904; US 7700580 B2 20100420

INPADOC legal status


2011-09-21 [18D] APPLICATION DEEMED TO BE WITHDRAWN

- Effective date: 20110316

2008-02-20 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20080117

2007-10-24 [DAX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT (TO ANY COUNTRY) (DELETED)

2007-10-03 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20070725

2007-10-03 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR