Global Patent Index - EP 1838872 A2

EP 1838872 A2 2007-10-03 - CANCER-SPECIFIC SPANX-N MARKERS

Title (en)

CANCER-SPECIFIC SPANX-N MARKERS

Title (de)

KREBSSPEZIFISCHE SPANX-N-MARKER

Title (fr)

MARQUEURS SPANX-N SPECIFIQUES DU CANCER

Publication

EP 1838872 A2 (EN)

Application

EP 05854102 A

Priority

  • US 2005045317 W
  • US 63681104 P

Abstract (en)

[origin: WO2006065938A2] The invention provides SPANX polypeptides, nucleic acids and antibodies that are useful for detecting and treating cancer. The invention relates to a new subfamily of SPANX genes, SPANX-N1, SPANX-N2, SPANX-N3 SPANX-N4 and SPANX-N5. In contrast to the previously identified SPANX-A/D subfamily, expression of SPANX-N genes is not restricted to testis, and was detected in normal prostate, placenta, lung, colon, ovary and cervix tissues. Comparison of matched normal/tumor tissues revealed a predominant activation of only one member of the subfamily, SPANX-N1, in tumors, indicating that expression of this gene is diagnostic of cancer. Methods and reagents described herein permit detection and treatment of cancers associated with SPANX-N1 expression.

IPC 8 full level (invention and additional information)

C12Q 1/68 (2006.01)

CPC (invention and additional information)

C12Q 1/68 (2013.01); C12Q 1/6886 (2013.01); C12Q 2600/136 (2013.01)

Citation (search report)

See references of WO 2006065938A3

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

EPO simple patent family

WO 2006065938 A2 20060622; WO 2006065938 A3 20070208; AU 2005316532 A1 20060622; CA 2591918 A1 20060622; EP 1838872 A2 20071003

INPADOC legal status


2010-12-29 [18D] APPLICATION DEEMED TO BE WITHDRAWN

- Effective date: 20100701

2008-03-26 [DAX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT (TO ANY COUNTRY) (DELETED)

2008-03-05 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20080205

2007-10-03 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20070713

2007-10-03 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR