Global Patent Index - EP 1841754 A1

EP 1841754 A1 20071010 - N-[(4,5-DIPHENYL-2-THIENYL)METHYL]SULFONAMIDE DERIVATIVES, PREPARATION THEREOF AND THEIR THERAPEUTIC APPLICATION

Title (en)

N-[(4,5-DIPHENYL-2-THIENYL)METHYL]SULFONAMIDE DERIVATIVES, PREPARATION THEREOF AND THEIR THERAPEUTIC APPLICATION

Title (de)

N-[(4,5-DIPHENYL-2-THIENYL)METHYL]SULFONSÄUREAMIDDERIVATE, VERFAHREN ZU DEREN HERSTELLUNG UND DEREN THERAPEUTISCHE ANWENDUNG

Title (fr)

DERIVES DE N-[(4,5-DIPHENYL-2-THIENYL)METHYL]SULFONAMIDE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE

Publication

EP 1841754 A1 20071010 (FR)

Application

EP 06709122 A 20060118

Priority

  • FR 2006000115 W 20060118
  • FR 0500570 A 20050119

Abstract (en)

[origin: WO2006077320A1] The invention relates to compounds of formula (I) in which: X represents an -SO- or -SO<SUB>2</SUB>- group; R<SUB>1</SUB> representing: a (C<SUB>1</SUB>-C<SUB>7</SUB>) alkyl; a (C<SUB>3</SUB>-C<SUB>12</SUB>) non-aromatic carbocyclic radical; a (C<SUB>3</SUB>-C<SUB>7</SUB>) cycloalkylmethyl; an unsubstituted, mono-, di- or trisubstituted phenyl; a unsubstituted, mono-, di- or trisubstituted benzyl on the phenyl; a unsubstituted, mono-, di- or trisubstituted phenethyl on the phenyl; an unsubstituted, mono-, di- or trisubstituted naphtyl; a benzhydryl; a benzhydryl methyl, and; an aromatic heterocyclic radical, R<SUB>2</SUB> represents a hydrogen atom or a (C<SUB>1</SUB>-C<SUB>3</SUB>) alkyl group; R<SUB>3</SUB> represents an unsubstituted, mono-, di- or trisubstituted phenyl; R<SUB>4</SUB> represents an unsubstituted, mono-, di- or trisubstituted phenyl; n represents 0, 1 or 2, and; Alk represents a (C<SUB>1</SUB>-C<SUB>4</SUB>) alkyl. The invention also relates to a method for preparing the aforementioned compounds and to their therapeutic application.

IPC 8 full level

C07D 333/20 (2006.01); A61K 31/381 (2006.01); C07D 333/34 (2006.01); C07D 409/12 (2006.01)

CPC (source: EP KR US)

A61K 31/381 (2013.01 - KR); A61P 1/00 (2017.12 - EP); A61P 1/14 (2017.12 - EP); A61P 3/00 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 25/30 (2017.12 - EP); A61P 25/32 (2017.12 - EP); A61P 25/34 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 37/00 (2017.12 - EP); A61P 37/02 (2017.12 - EP); C07D 333/20 (2013.01 - EP US); C07D 333/24 (2013.01 - KR); C07D 333/34 (2013.01 - EP US); C07D 409/12 (2013.01 - EP US)

Citation (search report)

See references of WO 2006077320A1

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

Designated extension state (EPC)

AL BA HR MK YU

DOCDB simple family (publication)

FR 2880890 A1 20060721; FR 2880890 B1 20070330; AR 053116 A1 20070425; AU 2006207382 A1 20060727; BR PI0606450 A2 20090630; CA 2595045 A1 20060727; CN 101119985 A 20080206; EP 1841754 A1 20071010; IL 184487 A0 20071031; JP 2008527026 A 20080724; KR 20070107048 A 20071106; MX 2007008792 A 20070911; RU 2007131275 A 20090227; TW 200637838 A 20061101; US 2007287744 A1 20071213; US 7589120 B2 20090915; UY 29338 A1 20060831; WO 2006077320 A1 20060727

DOCDB simple family (application)

FR 0500570 A 20050119; AR P060100142 A 20060113; AU 2006207382 A 20060118; BR PI0606450 A 20060118; CA 2595045 A 20060118; CN 200680004978 A 20060118; EP 06709122 A 20060118; FR 2006000115 W 20060118; IL 18448707 A 20070708; JP 2007551704 A 20060118; KR 20077018890 A 20070817; MX 2007008792 A 20060118; RU 2007131275 A 20060118; TW 95101890 A 20060118; US 77555707 A 20070710; UY 29338 A 20060118