EP 1844056 A2 20071017 - SULFONAMIDO-MACROCYCLES AS TIE2 INHIBITORS
Title (en)
SULFONAMIDO-MACROCYCLES AS TIE2 INHIBITORS
Title (de)
SULFONAMID-MAKROZYKLEN ALS TIE2- INHIBITOREN
Title (fr)
SULFONAMIDE-MACROCYCLES COMME TIE2-INHIBITEURS
Publication
Application
Priority
- EP 2005013957 W 20051219
- EP 04090509 A 20041222
- EP 05820679 A 20051219
Abstract (en)
[origin: EP1674470A1] The invention relates to sulfonamido-macrocycles according to the general Formula I and the salts thereof, to pharmaceutical compositions comprising the sulfonamido-macrocycles and to a method of preparing the sulfonamido-macrocycles as well as the use thereof for manufacturing a pharmaceutical composition for the treatment of diseases of dysregulated vascular growth or of diseases which are accompanied with dysregulated vascular growth, wherein the compounds effectively interfere with angiopoietin and therefore influence Tie2 signalling. wherein R 1 , R 2 and R 3 have the meaning as given in the specification and the claims.
IPC 8 full level
C07D 513/08 (2006.01)
CPC (source: EP KR)
A61P 1/00 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 9/12 (2017.12 - EP); A61P 11/00 (2017.12 - EP); A61P 13/08 (2017.12 - EP); A61P 15/00 (2017.12 - EP); A61P 17/02 (2017.12 - EP); A61P 17/06 (2017.12 - EP); A61P 19/08 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 27/02 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 35/04 (2017.12 - EP); A61P 37/08 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 513/08 (2013.01 - EP KR)
Citation (search report)
See references of WO 2006066957A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
EP 1674470 A1 20060628; AR 052175 A1 20070307; AU 2005318361 A1 20060629; BR PI0519268 A2 20090106; CA 2590742 A1 20060629; CN 101087798 A 20071212; EP 1844056 A2 20071017; GT 200500383 A 20060803; IL 182834 A0 20070819; JP 2008524303 A 20080710; KR 20070099619 A 20071009; NO 20073818 L 20070921; PA 8658001 A1 20060922; PE 20060881 A1 20061001; TW 200635935 A 20061016; WO 2006066957 A2 20060629; WO 2006066957 A3 20060831
DOCDB simple family (application)
EP 04090509 A 20041222; AR P050105399 A 20051221; AU 2005318361 A 20051219; BR PI0519268 A 20051219; CA 2590742 A 20051219; CN 200580044314 A 20051219; EP 05820679 A 20051219; EP 2005013957 W 20051219; GT 200500383 A 20051221; IL 18283407 A 20070426; JP 2007547386 A 20051219; KR 20077016661 A 20070720; NO 20073818 A 20070720; PA 8658001 A 20051222; PE 2006000007 A 20060103; TW 94145438 A 20051221