Global Patent Index - EP 1844056 A2

EP 1844056 A2 2007-10-17 - SULFONAMIDO-MACROCYCLES AS TIE2 INHIBITORS

Title (en)

SULFONAMIDO-MACROCYCLES AS TIE2 INHIBITORS

Title (de)

SULFONAMID-MAKROZYKLEN ALS TIE2- INHIBITOREN

Title (fr)

SULFONAMIDE-MACROCYCLES COMME TIE2-INHIBITEURS

Publication

EP 1844056 A2 (EN)

Application

EP 05820679 A

Priority

  • EP 2005013957 W
  • EP 04090509 A
  • EP 05820679 A

Abstract (en)

[origin: EP1674470A1] The invention relates to sulfonamido-macrocycles according to the general Formula I and the salts thereof, to pharmaceutical compositions comprising the sulfonamido-macrocycles and to a method of preparing the sulfonamido-macrocycles as well as the use thereof for manufacturing a pharmaceutical composition for the treatment of diseases of dysregulated vascular growth or of diseases which are accompanied with dysregulated vascular growth, wherein the compounds effectively interfere with angiopoietin and therefore influence Tie2 signalling. wherein R 1 , R 2 and R 3 have the meaning as given in the specification and the claims.

IPC 8 full level (invention and additional information)

C07D 513/08 (2006.01)

CPC (invention and additional information)

C07D 513/08 (2013.01)

Citation (search report)

See references of WO 2006066957A3

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

EPO simple patent family

EP 1674470 A1 20060628; AR 052175 A1 20070307; AU 2005318361 A1 20060629; BR PI0519268 A2 20090106; CA 2590742 A1 20060629; CN 101087798 A 20071212; EP 1844056 A2 20071017; GT 200500383 A 20060803; IL 182834 D0 20070819; JP 2008524303 A 20080710; KR 20070099619 A 20071009; PA 8658001 A1 20060922; PE 08812006 A1 20061001; TW 200635935 A 20061016; WO 2006066957 A2 20060629; WO 2006066957 A3 20060831

INPADOC legal status


2010-12-22 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20100630

2008-04-02 [DAX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT (TO ANY COUNTRY) DELETED

2008-01-23 [RIN1] INVENTOR (CORRECTION)

- Inventor name: KETTSCHAU, GEORG

2008-01-23 [RIN1] INVENTOR (CORRECTION)

- Inventor name: BRIEM, HANS

2008-01-23 [RIN1] INVENTOR (CORRECTION)

- Inventor name: LUECKING, ULRICH

2008-01-23 [RIN1] INVENTOR (CORRECTION)

- Inventor name: SCHAEFER, MARTINA

2008-01-23 [RIN1] INVENTOR (CORRECTION)

- Inventor name: THIERAUCH, KARL-HEINZ

2008-01-23 [RIN1] INVENTOR (CORRECTION)

- Inventor name: SCHWEDE, WOLFGANG

2008-01-23 [RIN1] INVENTOR (CORRECTION)

- Inventor name: HUSEMANN, MANFRED

2008-01-23 [RIN1] INVENTOR (CORRECTION)

- Inventor name: HUTH, ANDREAS

2007-10-17 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20070419

2007-10-17 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR