EP 1846424 B1 20100127 - PROTEASOME INHIBITORS AND METHODS OF USING THE SAME
Title (en)
PROTEASOME INHIBITORS AND METHODS OF USING THE SAME
Title (de)
PROTEASOM-HEMMER UND VERWENDUNGSVERFAHREN DAFÜR
Title (fr)
INHIBITEURS DU PROTEASOME ET LEURS METHODES D'UTILISATION
Publication
Application
Priority
- US 2006004664 W 20060210
- US 65237005 P 20050211
- US 35119306 A 20060209
Abstract (en)
[origin: US8283367B2] The present invention provides boronic acid compounds, boronic esters, and compositions thereof that can modulate apoptosis such as by inhibition of proteasome activity. The compounds and compositions can be used in methods of inducing apoptosis and treating diseases such as cancer and other disorders associated directly or indirectly with proteasome activity.
IPC 8 full level
C07F 5/02 (2006.01); A61K 31/69 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01)
CPC (source: EP US)
A61P 1/00 (2018.01 - EP); A61P 11/06 (2018.01 - EP); A61P 17/06 (2018.01 - EP); A61P 19/02 (2018.01 - EP); A61P 19/10 (2018.01 - EP); A61P 29/00 (2018.01 - EP); A61P 31/04 (2018.01 - EP); A61P 31/18 (2018.01 - EP); A61P 35/00 (2018.01 - EP); A61P 35/02 (2018.01 - EP); A61P 37/02 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07F 5/025 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2006086600 A1 20060817; AT E456571 T1 20100215; AU 2006213814 A1 20060817; AU 2006213814 B2 20111013; CA 2597273 A1 20060817; CA 2597273 C 20131217; CY 1109985 T1 20140910; DE 602006012013 D1 20100318; DK 1846424 T3 20100517; EP 1846424 A1 20071024; EP 1846424 B1 20100127; ES 2339698 T3 20100524; HK 1106534 A1 20080314; IL 184678 A0 20071203; IL 184678 A 20120531; JP 2008530108 A 20080807; MX 2007009664 A 20070926; MY 147921 A 20130215; NZ 560607 A 20091127; PL 1846424 T3 20100630; PT 1846424 E 20100415; SI 1846424 T1 20100531; TW 200640936 A 20061201; TW I367886 B 20120711; US 2006189806 A1 20060824; US 2009075936 A1 20090319; US 7468383 B2 20081223; US 8283367 B2 20121009
DOCDB simple family (application)
US 2006004664 W 20060210; AT 06734698 T 20060210; AU 2006213814 A 20060210; CA 2597273 A 20060210; CY 101100375 T 20100427; DE 602006012013 T 20060210; DK 06734698 T 20060210; EP 06734698 A 20060210; ES 06734698 T 20060210; HK 07112239 A 20071109; IL 18467807 A 20070717; JP 2007555228 A 20060210; MX 2007009664 A 20060210; MY PI20060567 A 20060210; NZ 56060706 A 20060210; PL 06734698 T 20060210; PT 06734698 T 20060210; SI 200630615 T 20060210; TW 95104473 A 20060210; US 26599808 A 20081106; US 35119306 A 20060209