EP 1848273 A4 20100224 - 18-MEMBERED MACROCYCLES AND ANALOGS THEREOF
Title (en)
18-MEMBERED MACROCYCLES AND ANALOGS THEREOF
Title (de)
18-GLIEDRIGE MAKROCYCLEN UND IHRE ANALOGA
Title (fr)
MACROCYCLES A 18 CHAINONS ET LEURS ANALOGUES
Publication
Application
Priority
US 2005002887 W 20050131
Abstract (en)
[origin: WO2006085838A1] The present invention relates generally to the 18-membered macrocyclic antimicrobial agents called Tiacumicins, specifically, OPT-80 (which is composed almost entirely of the R-Tiacumicin B), pharmaceutical compositions comprising OPT-80, and methods using OPT-80. In particular, this compound is a potent drug for the treatment of bacterial infections, specifically C. difficile infections.
IPC 8 full level
A01N 43/04 (2006.01); A61K 31/70 (2006.01); A61P 31/04 (2006.01)
CPC (source: EP KR)
A01N 43/22 (2013.01 - EP); A61K 31/365 (2013.01 - KR); A61K 31/436 (2013.01 - KR); A61K 31/70 (2013.01 - EP); A61P 1/12 (2017.12 - EP); A61P 31/00 (2017.12 - EP); A61P 31/04 (2017.12 - EP); A61P 31/10 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07H 17/08 (2013.01 - EP)
Citation (search report)
- [DXY] WO 2004014295 A2 20040219 - OPTIMER PHARMACEUTICALS INC [US], et al
- [Y] US 4918174 A 19900417 - MCALPINE JAMES B [US], et al
- [XY] CREDITO K L ET AL: "Activity of OPT-80, a novel macrocycle, compared with those of eight other agents against selected anaerobic species", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 200411 US, vol. 48, no. 11, November 2004 (2004-11-01), pages 4430 - 4434, XP002563520, ISSN: 0066-4804
- [Y] ARNONE A ET AL: "STRUCTURE ELUCIDATION OF THE MACROCYCLIC ANTIBIOTIC LIPIARMYCIN", JOURNAL OF THE CHEMICAL SOCIETY, PERKIN TRANSACTIONS 1, CHEMICAL SOCIETY, LETCHWORTH; GB, 1 January 1987 (1987-01-01), pages 1353 - 1359, XP000578201, ISSN: 0300-922X
- See references of WO 2006085838A1
Citation (examination)
WO 2005112990 A2 20051201 - OPTIMER PHARMACEUTICALS INC [US], et al
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR LV MK YU
DOCDB simple family (publication)
WO 2006085838 A1 20060817; AU 2005327308 A1 20060817; AU 2005327308 B2 20111110; BR PI0519890 A2 20090331; CA 2596387 A1 20060817; CA 2596387 C 20121120; CN 101128114 A 20080220; CN 101128114 B 20120328; CN 102614207 A 20120801; CN 102614207 B 20160113; EP 1848273 A1 20071031; EP 1848273 A4 20100224; JP 2008528582 A 20080731; JP 5166040 B2 20130321; KR 101203118 B1 20121120; KR 20070110504 A 20071119; MX 2007009196 A 20090225; MX 340742 B 20160721; TW 200626585 A 20060801; TW I306097 B 20090211
DOCDB simple family (application)
US 2005002887 W 20050131; AU 2005327308 A 20050131; BR PI0519890 A 20050131; CA 2596387 A 20050131; CN 200580048715 A 20050131; CN 201210032395 A 20050131; EP 05712354 A 20050131; JP 2007553073 A 20050131; KR 20077019982 A 20050131; MX 2007009196 A 20050131; MX 2012009525 A 20050131; TW 94115942 A 20050517