EP 1848449 A2 20071031 - BIOACTIVE COMPLEX OF TRITERPENE ACIDS, ITS PRODUCTION PROCESS AND MEDICINAL PRODUCTS WITH THERAPEUTICAL USES
Title (en)
BIOACTIVE COMPLEX OF TRITERPENE ACIDS, ITS PRODUCTION PROCESS AND MEDICINAL PRODUCTS WITH THERAPEUTICAL USES
Title (de)
BIOAKTIVER KOMPLEX AUS TRITERPENSÄUREN, HERSTELLUNGSVERFAHREN DAFÜR UND MEDIZINISCHE ARTIKEL ZUR THERAPEUTISCHEN VERWENDUNG
Title (fr)
COMPLEXE BIOACTIF D'ACIDES TRITERPENIQUES, SON PROCEDE DE PRODUCTION ET PRODUITS MEDICINAUX A USAGES THERAPEUTIQUES
Publication
Application
Priority
- RO 2006000003 W 20060215
- RO 200500117 A 20050218
Abstract (en)
[origin: WO2006088385A2] The invention relates to a bioactive complex of triterpene acids, as such or in the form of Na, K, NH4 salts of minimum 90 % purity, with a standardized content formed of: minimum 75 % ursolic acid, 10...15 oleanolic acid and 4...10 % other triterpene acids consisting of one or more of the following acids: hydroxyursolic, hydroxyoleanolic, betulinic, dehydrobetulinic, produced from the plants Salvia sp., Lavandula sp., Sambucus nigra and Crataegus sp. The production process recommends increase of selectivity and efficiencies of extraction, purification and crystallization steps by using structured waters ("I" - acid pH water and "S" - alkaline pH water) in the composition of solvents used. The bioactive complex of triterpene acids has a marked and diversified pharmacological activity for bioregulating proteinic, glucidic and lipidic metabolism, particularly on aged organisms, as well as immunoprotective, antioxidizing, hepatoprotective, and retarding activity in tumour progression, being conditioned as new medicinal products for internal and/or external use with applicability in human and veterinary therapy.
IPC 8 full level
A61K 36/00 (2006.01)
CPC (source: EP)
A61K 31/19 (2013.01); A61K 36/35 (2013.01); A61K 36/53 (2013.01); A61K 36/537 (2013.01); A61K 36/734 (2013.01)
C-Set (source: EP)
Citation (search report)
See references of WO 2006088385A2
Designated contracting state (EPC)
DE FR GB IT
DOCDB simple family (publication)
WO 2006088385 A2 20060824; WO 2006088385 A3 20061228; EP 1848449 A2 20071031; RO 120950 B1 20061030
DOCDB simple family (application)
RO 2006000003 W 20060215; EP 06716833 A 20060215; RO 200500117 A 20050218