EP 1848720 A1 20071031 - RAPID RESOLUTION PROCESS FOR CLOPIDOGREL BASE AND A PROCESS FOR PREPARATION OF CLOPIDOGREL BISULFATE POLYMORPH - FORM I
Title (en)
RAPID RESOLUTION PROCESS FOR CLOPIDOGREL BASE AND A PROCESS FOR PREPARATION OF CLOPIDOGREL BISULFATE POLYMORPH - FORM I
Title (de)
SCHNELLES VERFAHREN ZUR OPTISCHEN TRENNUNG VON CLOPIDOGREL-BASE UND VERFAHREN ZUR HERSTELLUNG DER CLOPIDOGRELBISULFATPOLYMORPHFORM I
Title (fr)
PROCEDE DE RESOLUTION RAPIDE DESTINE A UNE BASE DE CLOPIDOGREL ET PROCEDE DE PREPARATION DE LA FORME I POLYMORPHIQUE DE L'HYDROGENOSULFATE DE CLOPIDOGREL
Publication
Application
Priority
IN 2005000048 W 20050215
Abstract (en)
[origin: WO2006087729A1] The present invention discloses a rapid resolution process of racemic clopidogrel base followed by conversion of the resolved (S) isomer to crystalline Clopidogrel bisulfate Form I. The invention also discloses novel racemization process of the unwanted (R) isomer of clopidogrel base. The invention further discloses an improved process for preparation of acid addition salts of clopidogrel.
IPC 8 full level
C07D 495/04 (2006.01)
CPC (source: EP)
C07D 495/04 (2013.01)
Citation (search report)
See references of WO 2006087729A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR LV MK YU
DOCDB simple family (publication)
WO 2006087729 A1 20060824; WO 2006087729 B1 20061109; AU 2005327776 A1 20060824; CA 2567806 A1 20060824; CA 2567806 C 20110426; EP 1848720 A1 20071031
DOCDB simple family (application)
IN 2005000048 W 20050215; AU 2005327776 A 20050215; CA 2567806 A 20050215; EP 05747156 A 20050215