Global Patent Index - EP 1848720 A1

EP 1848720 A1 2007-10-31 - RAPID RESOLUTION PROCESS FOR CLOPIDOGREL BASE AND A PROCESS FOR PREPARATION OF CLOPIDOGREL BISULFATE POLYMORPH - FORM I

Title (en)

RAPID RESOLUTION PROCESS FOR CLOPIDOGREL BASE AND A PROCESS FOR PREPARATION OF CLOPIDOGREL BISULFATE POLYMORPH - FORM I

Title (de)

SCHNELLES VERFAHREN ZUR OPTISCHEN TRENNUNG VON CLOPIDOGREL-BASE UND VERFAHREN ZUR HERSTELLUNG DER CLOPIDOGRELBISULFATPOLYMORPHFORM I

Title (fr)

PROCEDE DE RESOLUTION RAPIDE DESTINE A UNE BASE DE CLOPIDOGREL ET PROCEDE DE PREPARATION DE LA FORME I POLYMORPHIQUE DE L'HYDROGENOSULFATE DE CLOPIDOGREL

Publication

EP 1848720 A1 (EN)

Application

EP 05747156 A

Priority

IN 2005000048 W

Abstract (en)

[origin: WO2006087729A1] The present invention discloses a rapid resolution process of racemic clopidogrel base followed by conversion of the resolved (S) isomer to crystalline Clopidogrel bisulfate Form I. The invention also discloses novel racemization process of the unwanted (R) isomer of clopidogrel base. The invention further discloses an improved process for preparation of acid addition salts of clopidogrel.

IPC 8 full level (invention and additional information)

C07D 495/04 (2006.01)

CPC (invention and additional information)

C07D 495/04 (2013.01)

Citation (search report)

See references of WO 2006087729A1

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR

Designated extension state (EPC)

AL BA HR LV MK YU

EPO simple patent family

WO 2006087729 A1 20060824; WO 2006087729 B1 20061109; AU 2005327776 A1 20060824; CA 2567806 A1 20060824; CA 2567806 C 20110426; EP 1848720 A1 20071031

INPADOC legal status


2012-12-19 [18D] APPLICATION DEEMED TO BE WITHDRAWN

- Effective date: 20120626

2009-12-30 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20091125

2007-10-31 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20070814

2007-10-31 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR

2007-10-31 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO:

- Countries: AL BA HR LV MK YU