Global Patent Index - EP 1848981 A2

EP 1848981 A2 2007-10-31 - METHOD FOR DETERMINING REDOX ACTIVITY AND SCREENING COMPOUNDS BASED ON REDOX ACTIVITY

Title (en)

METHOD FOR DETERMINING REDOX ACTIVITY AND SCREENING COMPOUNDS BASED ON REDOX ACTIVITY

Title (de)

VERFAHREN ZUR BESTIMMUNG EINER REDOX-AKTIVITÄT UND SCREENING-VERBINDUNGEN AUF BASIS EINER REDOX-AKTIVITÄT

Title (fr)

PROCEDE DESTINE A DETERMINER L'ACTIVITE OXYDOREDUCTRICE ET COMPOSES DE CRIBLAGE BASES SUR L'ACTIVITE OXYDOREDUCTRICE

Publication

EP 1848981 A2 (EN)

Application

EP 06734783 A

Priority

  • US 2006004803 W
  • US 65173005 P
  • US 34093806 A

Abstract (en)

[origin: WO2006086670A2] A method for identifying the redox activity of a subject compound is disclosed. The method can be performed aerobically and can include forming a mixture comprising a free-radical precursor and a compound to be tested, and converting the free-radical precursor into a free-radical anion and a free-radical cation. After the free radical cation and the free radical anion have been formed, the relative redox activity of the subject compound may cause a difference in the rate of photo-bleaching of the mixture and/or the rate of superoxide generation. These differences can be quantified and used to identify the redox activity of the subject compound. This sensitive technique for measuring redox activity can be used to screen compounds for various biological applications. Drugs also can be developed based on the relationship between redox activity and biological activity for particular biological applications.

IPC 8 full level (invention and additional information)

G01N 21/27 (2006.01); G01N 21/00 (2006.01); G01N 21/77 (2006.01); G01N 31/22 (2006.01)

CPC (invention and additional information)

G01N 31/224 (2013.01); G01N 21/272 (2013.01); G01N 21/77 (2013.01); G01N 2021/6439 (2013.01)

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

EPO simple patent family

WO 2006086670 A2 20060817; WO 2006086670 A3 20070111; EP 1848981 A2 20071031; EP 1848981 A4 20120118

INPADOC legal status


2013-01-09 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20120717

2012-01-18 [A4] SUPPLEMENTARY SEARCH REPORT

- Effective date: 20111219

2012-01-18 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: G01N 21/27 20060101AFI20111213BHEP

2012-01-18 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: G01N 21/77 20060101ALI20111213BHEP

2012-01-18 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: G01N 31/22 20060101ALI20111213BHEP

2012-01-18 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: G01N 21/00 20060101ALI20111213BHEP

2008-05-14 [DAX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT (TO ANY COUNTRY) DELETED

2007-10-31 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20070829

2007-10-31 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR