EP 1853234 A2 20071114 - AEROSOL AND INJECTABLE FORMULATIONS OF NANOPARTICULATE BENZODIAZEPINE
Title (en)
AEROSOL AND INJECTABLE FORMULATIONS OF NANOPARTICULATE BENZODIAZEPINE
Title (de)
AEROSOL UND INJIZIERBARE FORMULIERUNGEN AUS BENZODIAZEPIN IN FORM VON NANOTEILCHEN
Title (fr)
FORMULATIONS AEROSOL ET INJECTABLES DE NANOPARTICULES DE BENZODIAZEPINE
Publication
Application
Priority
- US 2006005224 W 20060215
- US 65303405 P 20050215
Abstract (en)
[origin: WO2006088894A2] Described are nanoparticulate formulations of a benzodiazepine, such as lorazepam, that does not require the presence of polyethylene glycol and propylene glycol as stabilizers, and methods of making and using such formulations. The formulations are particularly useful in aerosol and injectable dosage forms, and comprise nanoparticulate benzodiazepine, such as lorazepam, and at least one surface stabilizer. The formulations are useful in the treatment of status epilepticus, treatment of irritable bowel syndrome, sleep induction, acute psychosis, and as a pre-anesthesia medication.
IPC 8 full level
A61K 9/72 (2006.01); A61K 9/10 (2006.01); A61K 9/14 (2006.01)
CPC (source: EP KR US)
A61K 9/0019 (2013.01 - EP US); A61K 9/0073 (2013.01 - EP US); A61K 9/10 (2013.01 - KR); A61K 9/14 (2013.01 - KR); A61K 9/145 (2013.01 - EP US); A61K 9/146 (2013.01 - EP US); A61K 31/5513 (2013.01 - EP US); A61P 1/00 (2018.01 - EP); A61P 23/00 (2018.01 - EP); A61P 25/00 (2018.01 - EP); A61P 25/08 (2018.01 - EP); A61P 25/18 (2018.01 - EP); A61P 25/20 (2018.01 - EP); A61K 9/0043 (2013.01 - EP US); B82Y 5/00 (2013.01 - KR)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK YU
DOCDB simple family (publication)
WO 2006088894 A2 20060824; WO 2006088894 A3 20061130; AU 2006214443 A1 20060824; AU 2006214443 B2 20110616; AU 2006214443 C1 20111124; BR PI0608087 A2 20091110; CA 2597716 A1 20060824; CN 101189001 A 20080528; EA 013433 B1 20100430; EA 200701731 A1 20080228; EP 1853234 A2 20071114; EP 2332524 A1 20110615; EP 2353590 A1 20110810; IL 185265 A0 20080605; JP 2008530134 A 20080807; KR 20070112164 A 20071122; MX 2007009915 A 20071106; NO 20074602 L 20071031; US 2006198896 A1 20060907; US 2009304801 A1 20091210; ZA 200707610 B 20081126
DOCDB simple family (application)
US 2006005224 W 20060215; AU 2006214443 A 20060215; BR PI0608087 A 20060215; CA 2597716 A 20060215; CN 200680012468 A 20060215; EA 200701731 A 20060215; EP 06735067 A 20060215; EP 11001511 A 20060215; EP 11001512 A 20060215; IL 18526507 A 20070814; JP 2007555348 A 20060215; KR 20077020820 A 20070911; MX 2007009915 A 20060215; NO 20074602 A 20070911; US 35424906 A 20060215; US 54419709 A 20090819; ZA 200707610 A 20070904