EP 1855523 A4 20100623 - INSULIN AND LEPTIN RESISTANCE WITH HYPERLEPTINEMIA IN MICE LACKING ANDROGEN RECEPTOR
Title (en)
INSULIN AND LEPTIN RESISTANCE WITH HYPERLEPTINEMIA IN MICE LACKING ANDROGEN RECEPTOR
Title (de)
INSULIN- UND LEPTIN-BESTÄNDIGKEIT MIT HYPERLEPTINÄMIE BEI MÄUSEN OHNE ANDROGENREZEPTOREN
Title (fr)
RESISTANCE A L'INSULINE ET LA LEPTINE AVEC DE L'HYPERLETPTINEMIE DANS DES SOURIS DEFICIENTES EN RECEPTEUR D'ANDROGENE
Publication
Application
Priority
- US 2006000474 W 20060106
- US 64212905 P 20050107
Abstract (en)
[origin: WO2006074378A2] Disclosed are compositions and methods for related to diabetes and coronary heart disease.
IPC 8 full level
A01K 67/00 (2006.01); G01N 15/00 (2006.01)
CPC (source: EP)
A01K 67/0276 (2013.01); C07K 14/721 (2013.01); G01N 33/5088 (2013.01); A01K 2217/075 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0362 (2013.01); C12N 2800/30 (2013.01); G01N 2333/723 (2013.01); G01N 2800/042 (2013.01); G01N 2800/32 (2013.01)
Citation (search report)
- [Y] WO 03012394 A2 20030213 - UNIV ROCHESTER [US], et al
- [A] WO 03100028 A2 20031204 - UNIV ROCHESTER [US], et al
- [Y] SATO TAKASHI ET AL: "Late onset of obesity in male androgen receptor-deficient (AR KO) mice.", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 3 JAN 2003 LNKD- PUBMED:12480537, vol. 300, no. 1, 3 January 2003 (2003-01-03), pages 167 - 171, XP002581152, ISSN: 0006-291X
- [Y] ZITZMANN M ET AL: "The CAG repeat polymorphism in the androgen receptor gene modulates body fat mass and serum concentrations of leptin and insulin in men.", DIABETOLOGIA JAN 2003 LNKD- PUBMED:12637980, vol. 46, no. 1, January 2003 (2003-01-01), pages 31 - 39, XP002581153, ISSN: 0012-186X
- [A] MAYES J S ET AL: "Direct effects of sex steroid hormones on adipose tissues and obesity.", OBESITY REVIEWS : AN OFFICIAL JOURNAL OF THE INTERNATIONAL ASSOCIATION FOR THE STUDY OF OBESITY NOV 2004 LNKD- PUBMED:15458395, vol. 5, no. 4, November 2004 (2004-11-01), pages 197 - 216, XP002581154, ISSN: 1467-7881
- [XP] FAN WUQIANG ET AL: "Androgen receptor null male mice develop late-onset obesity caused by decreased energy expenditure and lipolytic activity but show normal insulin sensitivity with high adiponectin secretion", DIABETES, vol. 54, no. 4, April 2005 (2005-04-01), pages 1000 - 1008, XP002581155, ISSN: 0012-1797
- [A] ALEVIZAKI M ET AL: "The androgen receptor gene CAG polymorphism is associated with the severity of coronary artery disease in men.", CLINICAL ENDOCRINOLOGY DEC 2003 LNKD- PUBMED:14974917, vol. 59, no. 6, December 2003 (2003-12-01), pages 749 - 755, XP002581156, ISSN: 0300-0664
- See references of WO 2006074378A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2006074378 A2 20060713; WO 2006074378 A3 20070308; AU 2006203870 A1 20060713; CA 2596783 A1 20060713; EP 1855523 A2 20071121; EP 1855523 A4 20100623
DOCDB simple family (application)
US 2006000474 W 20060106; AU 2006203870 A 20060106; CA 2596783 A 20060106; EP 06717647 A 20060106