Global Patent Index - EP 1858505 A2

EP 1858505 A2 20071128 - POLYACETYLEN COMPOUNDS ISOLATED FROM CUSSONIA

Title (en)

POLYACETYLEN COMPOUNDS ISOLATED FROM CUSSONIA

Title (de)

AUS CUSSONIA ISOLIERTE POLYACETYLEN-VERBINDUNGEN

Title (fr)

COMPOSES DE POLYACETYLENE ISOLES A PARTIR DE CUSSONIA

Publication

EP 1858505 A2 20071128 (EN)

Application

EP 05825898 A 20051222

Priority

  • IB 2005003903 W 20051222
  • GB 0428164 A 20041223

Abstract (en)

[origin: WO2006067607A2] The present invention relates to certain linear polyacetylene containing compounds which are indicated as having a positive allosteric modulating activity on the GABA<SUB>A</SUB> receptor. More specifically the invention relates to linear polyacetylene containing compounds having a ß-subunit selective, positive allosteric modulating activity on the GABA<SUB>A</SUB> receptor and substantially lacking a binding capability at the benzodiazepine binding site, their use as agents for the treatment of diseases of the central nervous system (CNS) in mammals, such as humans, and in particular in the treatment of CNS diseases, such as anxiety and epilepsy.

IPC 8 full level

A61K 31/22 (2006.01); A61K 36/25 (2006.01); A61P 25/22 (2006.01)

CPC (source: EP)

A61K 31/22 (2013.01); A61K 36/25 (2013.01); A61P 25/22 (2018.01)

Citation (search report)

See references of WO 2006067607A3

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

DOCDB simple family (publication)

WO 2006067607 A2 20060629; WO 2006067607 A3 20061130; EP 1858505 A2 20071128; GB 0428164 D0 20050126

DOCDB simple family (application)

IB 2005003903 W 20051222; EP 05825898 A 20051222; GB 0428164 A 20041223