EP 1858923 A4 20081015 - A MOLECULE AND CHIMERIC MOLECULES THEREOF
Title (en)
A MOLECULE AND CHIMERIC MOLECULES THEREOF
Title (de)
MOLEKÜL UND CHIMÄRE MOLEKÜLE DAVON
Title (fr)
MOLÉCULE ET MOLÉCULES CHIMÈRES DE CELLE-CI
Publication
Application
Priority
- AU 2006000190 W 20060214
- AU 2005906337 A 20051115
- AU 2005906549 A 20051123
- US 65328505 P 20050214
- US 65401705 P 20050216
- US 66246605 P 20050315
- US 66251705 P 20050315
- US 67556705 P 20050427
- US 67950405 P 20050510
- US 68037505 P 20050512
Abstract (en)
[origin: WO2006084337A1] The present invention relates generally to the fields of proteins, diagnostics, therapeutics and nutrition. More particularly, the present invention provides an isolated protein molecule that comprises a dimeric 4-helix bundle, such as IFN-a2B, IFN-b1, IFN-g, IL-10 or its receptor, such as IFNAR2, IL-10Ra or chimeric molecules thereof comprising at least a portion of the protein molecule, such as IFN-a2B-Fc, IFN-bl -Fc, IFN-g-Fc, IFNAR2-Fc, IL-IO-Fc, IL-10Ra-Fc; wherein the protein or chimeric molecule thereof has a profile of measurable physiochemical parameters, wherein the profile is indicative of, associated with or forms the basis of one or more pharmacological traits. The present invention further contemplates the use of the isolated protein or chimeric molecule thereof in a range of diagnostic, prophylactic, therapeutic, nutritional and/or research applications.
IPC 8 full level
A61K 38/17 (2006.01); A61K 38/20 (2006.01); A61K 38/21 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61P 31/00 (2006.01); A61P 35/00 (2006.01); A61P 37/00 (2006.01); C07H 21/04 (2006.01); C07K 14/54 (2006.01); C07K 14/57 (2006.01); C07K 14/715 (2006.01); C07K 19/00 (2006.01); G01N 33/543 (2006.01)
CPC (source: EP)
A61P 31/00 (2017.12); A61P 35/00 (2017.12); A61P 37/00 (2017.12); C07K 14/5428 (2013.01); C07K 14/555 (2013.01); G01N 33/6866 (2013.01); G01N 33/6869 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
- No further relevant documents disclosed
- See references of WO 2006084337A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2006084337 A1 20060817; CA 2597346 A1 20060817; EP 1858923 A1 20071128; EP 1858923 A4 20081015; JP 2008536477 A 20080911
DOCDB simple family (application)
AU 2006000190 W 20060214; CA 2597346 A 20060214; EP 06704867 A 20060214; JP 2007554393 A 20060214