EP 1866648 A2 20071219 - POLYPEPTIDE MARKERS FOR THE DIAGNOSIS OF PROSTATE CANCER
Title (en)
POLYPEPTIDE MARKERS FOR THE DIAGNOSIS OF PROSTATE CANCER
Title (de)
POLYPEPTIDMARKER ZUR DIAGNOSE VON PROSTATAKREBS
Title (fr)
MARQUEURS POLYPEPTIDIQUES POUR DIAGNOSTIQUER LE CANCER DE LA PROSTATE
Publication
Application
Priority
- EP 2006061374 W 20060406
- EP 05102741 A 20050407
- EP 05105434 A 20050621
- EP 06725599 A 20060406
Abstract (en)
[origin: WO2006106129A2] The invention relates to a method for the diagnosis of prostate cancer. According to said method, the presence or absence of at least three polypeptide markers in a sample is determined, said polypeptide markers being selected from the markers 1 to 44 and 52 to 78 (frequency marker), or the amplitude of at least one polypeptide marker, selected from the markers 45 to 51 and 79 to 115 (amplitude marker) is determined, said markers being characterised by the following values of the molecular masses and the migration time: number/mass [Da]/migration time number/mass [Da]/migration time 1 1579,7 26,4 27 1180,5 33,9 2 1991,9 17,1 28 2421,1 32,5 3 1955,9 24,8 29 4345,9 30,6 4 1140,5 21,4 30 2077,1 16,9 5 1677,3 7,4 31 1134,6 19,4 6 10753,1 13,6 32 1444,8 13,5 7 1412,6 22,1 33 1046,5 21,9 8 1636,8 27,2 34 1992,2 16,8 9 1946,9 28,4 35 4069,6 21,3 10 5887,6 25,1 36 1191,5 34,5 11 12407,9 22,2 37 1239,5 32,5 12 1186,6 17,4 38 2191,9 17,2 13 1240,6 23,3 39 1865,8 30,0 14 1326,6 24,8 40 1265,6 23,4 15 3802,1 30,1 41 1936,1 10,5 16 1749,9 19,4 42 911,3 31,9 17 2216,1 31,0 43 1494,7 26,4 18 1069,5 22,7 44 1209,6 22,5 19 1341,6 26,6 45 1193,3 34,2 20 1353,7 21,8 46 1235,4 34,3 21 1716,8 24,6 47 1390,5 35,0 22 2939,1 31,1 48 2292,1 23,7 23 3002,0 19,2 49 2736,3 17,1 24 1110,4 31,5 50 3385,5 21,0 25 1496,7 26,5 51 3945,2 21,4 26 1825,8 28,4 - 34 - number/mass [Da]/migration time number/mass [Da]/migration time 52 1636,8 27,2 66 1878, 9 15, 3 53 1412,6 22,1 67 3593, 4 14, 5 54 1579,7 26,4 68 1236, 7 13, 3 55 1390,5 35,0 69 2736, 3 17, 1 56 1196,6 15,8 70 2973, 4 20, 0 57 11041,4 16,6 71 1134, 6 19, 4 58 2971,4 17,9 72 2191, 9 17, 2 59 3136,6 20,0 73 2205, 1 25, 1 60 4409,9 14,2 74 3959, 7 14, 0 61 1494,7 26,4 75 1749, 9 19, 4 62 1833,9 24,2 76 4069, 6 21, 3 63 2752,4 14,0 77 2816, 3 24, 7 64 3515,8 15,3 78 3435, 8 15, 0 65 1082,5 17,7 - 35 - number/mass [Da]/migration time number/mass [Da]/migration time 79 973,26 35,44 80 1128,54 25,66 81 1173,58 37,47 82 1184,6 26,43 83 1290,39 30,85 84 1338,66 23,96 85 1428,45 36,73 86 1450,6 37,47 87 1460,71 19,83 88 1498,46 35,31 89 1526,76 23,54 90 1588,77 30,24 91 1675,77 29,23 92 1703,91 33,67 93 1808,87 23,72 94 1863,96 44,01 95 1867,79 33,29 96 1925,9 23,2 97 2036,97 31,53 98 2114,05 31,59 99 2196,11 33,16 100 2212,06 33,36 101 2257,95 36,02 102 2544,06 26,14 103 2599,21 28,05 104 2761,38 21,47 105 3334,17 31,01 106 3361,41 24,32 107 3426,43 27,73 108 3765,51 20,18 109 3864,56 33,82 110 3870,8 33,47 111 4252,03 28,77 112 6211,93 20,27 113 6650,86 25,55 114 6820,37 21,03 115 16918,24 19,8. The sample taken is a sample of urine or semen.
IPC 8 full level
G01N 33/574 (2006.01); G01N 33/68 (2006.01)
CPC (source: EP US)
G01N 33/57434 (2013.01 - EP US); G01N 33/6848 (2013.01 - EP US)
Citation (search report)
See references of WO 2006106129A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK YU
DOCDB simple family (publication)
WO 2006106129 A2 20061012; WO 2006106129 A3 20070920; AU 2006231611 A1 20061012; AU 2006231611 B2 20121206; BR PI0607016 A2 20090804; CA 2604037 A1 20061012; EP 1866648 A2 20071219; EP 2317320 A2 20110504; EP 2317320 A3 20110713; JP 2008537112 A 20080911; US 2009298184 A1 20091203; US 2015133343 A1 20150514
DOCDB simple family (application)
EP 2006061374 W 20060406; AU 2006231611 A 20060406; BR PI0607016 A 20060406; CA 2604037 A 20060406; EP 06725599 A 20060406; EP 10183096 A 20060406; JP 2008504769 A 20060406; US 201414584146 A 20141229; US 88756206 A 20060406