EP 1870395 A1 20071226 - Process for preparation of o-desmethylvenlafaxine and its analogue
Title (en)
Process for preparation of o-desmethylvenlafaxine and its analogue
Title (de)
Verfahren zur Herstellung von o-Desmethylvenlafaxin und seiner Analoga
Title (fr)
Procédé pour fabriquer de l'o-Desmethylvenlafaxine et de ses analogues
Publication
Application
Priority
EP 06012531 A 20060619
Abstract (en)
The present invention belongs to the field of organic chemistry and refers to a process for the preparation of O -desmethylvenlafaxine (1-[2-Dimethylamino)-1-(4-hydroxyphenyl)ethyl]cyclohexanol) and its analogues. The invention also relates to a catalytic hydrogenation of cyano-group of the substituted acetonitrile.
IPC 8 full level
C07C 217/74 (2006.01); C07C 255/37 (2006.01)
CPC (source: EP)
C07C 213/02 (2013.01); C07C 215/64 (2013.01); C07C 217/74 (2013.01); C07C 2601/14 (2017.04)
Citation (search report)
- [Y] US 2003225127 A1 20031204 - BENDER DAVID MICHAEL [US], et al
- [X] US 2005033088 A1 20050210 - REGURI BUCHI REDDY [IN], et al
- [XY] DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; REGURI, BUCHI REDDY ET AL: "Hydrogenation and chemoselective methylation processes for the preparation of venlafaxine hydrochloride from 1-[cyano(p-methoxyphenyl)methyl]cyclohex anol", XP002419099, retrieved from STN Database accession no. 2006:913606 & IN 191960 A1
- [X] S. P. CHAVAN ET AL: "An efficient and green protocol for the preparation of cycloalkanols: apractical synthesis of venlafaxine", TETRAHEDRON LETTERS., vol. 45, 2004, NLELSEVIER, AMSTERDAM., pages 7291 - 7295, XP002419152
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK YU
DOCDB simple family (publication)
EP 1870395 A1 20071226; EP 2035366 A1 20090318; WO 2007147564 A1 20071227
DOCDB simple family (application)
EP 06012531 A 20060619; EP 07726080 A 20070619; EP 2007005394 W 20070619