EP 1871377 A1 20080102 - 2,4-DIAMINO-PYRIDOPYRIMIDINE DERIVATIVES AND THEIR USE AS MTOR INHIBITORS
Title (en)
2,4-DIAMINO-PYRIDOPYRIMIDINE DERIVATIVES AND THEIR USE AS MTOR INHIBITORS
Title (de)
2,4-DIAMINO-PYRIDOPYRIDIMIDIN-DERIVATE UND IHRE VERWENDUNG ALS MTOR-HEMMER
Title (fr)
DERIVES DE 2 , 4-DIAMINO-PYRIDOPYRIMIDINE ET LEUR UTILISATION COMME INHIBITEURS MTOR
Publication
Application
Priority
- GB 2006000671 W 20060224
- GB 0503961 A 20050225
- US 65617805 P 20050225
- US 74240305 P 20051205
Abstract (en)
[origin: WO2006090169A1] Compounds of formula (I) and isomers, salts, solvates, chemically protected forms, and prodrugs thereof one of X<SUP>1</SUP>, X<SUP>2</SUP> and X<SUP>3</SUP> is N, and the others are CH; R<SUP>N1</SUP> and R<SUP>N2</SUP> together with the nitrogen atom to which they are attached form a nitrogen-containing heterocyclic ring having from 4 to 8 ring atoms; R<SUP>N3</SUP> and R<SUP>N4</SUP> together with the nitrogen atom to which they are attached form a nitrogen-containing heterocyclic ring having from 4 to 8 ring atoms and their use in treating diseases ameliorated by the inhibition of mTOR.
IPC 8 full level
A61K 31/519 (2006.01); C07D 471/04 (2006.01)
CPC (source: EP KR)
A61K 31/519 (2013.01 - KR); A61P 1/00 (2017.12 - EP); A61P 1/16 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 17/06 (2017.12 - EP); A61P 19/02 (2017.12 - EP); A61P 19/08 (2017.12 - EP); A61P 27/02 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 31/10 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 37/00 (2017.12 - EP); A61P 37/02 (2017.12 - EP); A61P 37/04 (2017.12 - EP); A61P 37/06 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 471/04 (2013.01 - EP KR)
Citation (search report)
See references of WO 2006090169A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2006090169 A1 20060831; AU 2006217744 A1 20060831; CA 2599212 A1 20060831; EP 1871377 A1 20080102; IL 184901 A0 20071203; JP 2008531538 A 20080814; KR 20070113252 A 20071128; MX 2007010401 A 20080219; NO 20074057 L 20070917
DOCDB simple family (application)
GB 2006000671 W 20060224; AU 2006217744 A 20060224; CA 2599212 A 20060224; EP 06709898 A 20060224; IL 18490107 A 20070729; JP 2007556665 A 20060224; KR 20077021848 A 20070921; MX 2007010401 A 20060224; NO 20074057 A 20070807