Global Patent Index - EP 1874223 B1

EP 1874223 B1 20130807 - ELASTIN STABILIZATION OF CONNECTIVE TISSUE

Title (en)

ELASTIN STABILIZATION OF CONNECTIVE TISSUE

Title (de)

ELASTINSTABILISIERUNG VON BINDEGEWEBE

Title (fr)

STABILISATION DE L'ELASTINE DU TISSU CONJONCTIF

Publication

EP 1874223 B1 20130807 (EN)

Application

EP 06758289 A 20060407

Priority

  • US 2006013090 W 20060407
  • US 67463105 P 20050425
  • US 38745406 A 20060323

Abstract (en)

[origin: US2006240066A1] A method and product are provided for the treatment of connective tissue weakened due to destruction of tissue architecture, and in particular due to elastin degradation. The treatment agents employ certain unique properties of phenolic compounds to develop a protocol for reducing elastin degradation, such as that occurring during aneurysm formation in vasculature. According to the invention, elastin can be stabilized in vivo and destruction of connective tissue, such as that leading to life-threatening aneurysms in vasculature, can be tempered or halted all together. The treatment agents can be delivered or administered acutely or chronically according to various delivery methods, including sustained release methods incorporating perivascular or endovascular patches, use of microsphere carriers, hydrogels, or osmotic pumps.

IPC 8 full level

A61K 31/7024 (2006.01); A61F 2/00 (2006.01); A61P 9/14 (2006.01)

CPC (source: EP US)

A61K 31/7024 (2013.01 - EP US); A61P 7/00 (2017.12 - EP); A61P 9/00 (2017.12 - EP); A61P 9/14 (2017.12 - EP); A61P 19/04 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 43/00 (2017.12 - EP)

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

DOCDB simple family (publication)

US 2006240066 A1 20061026; US 7252834 B2 20070807; CN 101208057 A 20080625; CN 101208057 B 20110615; CN 102225028 A 20111026; CN 102225028 B 20160224; EP 1874223 A2 20080109; EP 1874223 A4 20090513; EP 1874223 B1 20130807; EP 2460525 A1 20120606; EP 2460525 B1 20160713; EP 2460525 B8 20160914; JP 2008542195 A 20081127; JP 5282956 B2 20130904; US 2007281026 A1 20071206; US 2010185272 A1 20100722; US 2012114732 A1 20120510; US 7713543 B2 20100511; US 8100961 B2 20120124; US 8435553 B2 20130507; WO 2006115733 A2 20061102; WO 2006115733 A3 20061214

DOCDB simple family (application)

US 38745406 A 20060323; CN 200680022770 A 20060407; CN 201110096147 A 20060407; EP 06758289 A 20060407; EP 11181250 A 20060407; JP 2008508885 A 20060407; US 2006013090 W 20060407; US 201113333592 A 20111221; US 74884910 A 20100329; US 82712107 A 20070710