Global Patent Index - EP 1874734 A1

EP 1874734 A1 20080109 - 1H-IMIDAZOLE DERIVATIVES AS CANNABINOID CB2 RECEPTOR MODULATORS

Title (en)

1H-IMIDAZOLE DERIVATIVES AS CANNABINOID CB2 RECEPTOR MODULATORS

Title (de)

1H-IMIDAZOLDERIVATE ALS MODULATOREN DES CANNABINOID-CB2-REZEPTORS

Title (fr)

DERIVES 1H-IMIDAZOLE UTILES COMME DES MODULATEURS DU RECEPTEUR CANNABINOID CB2

Publication

EP 1874734 A1 20080109 (EN)

Application

EP 06708303 A 20060216

Priority

  • EP 2006060009 W 20060216
  • EP 05101171 A 20050216
  • US 65309105 P 20050216
  • EP 06708303 A 20060216

Abstract (en)

[origin: WO2006087355A1] The invention relates to a group of 1 H-imidazole derivatives which are modulators of cannabinoid CB<SUB>2</SUB> receptors, to methods for the preparation of these compounds, to novel intermediates useful for the synthesis of said imidazole derivatives, to methods for the preparation of these intermediates, to pharmaceutical compositions containing one or more of these 1 H-imidazole derivatives as active ingredient, as well as to the use of these pharmaceutical compositions for the treatment of disorders in which cannabinoid CB<SUB>2 </SUB>receptors are involved. The compounds have the general formula (I) wherein R<SUB>1</SUB>-R<SUB>4</SUB> have the meanings given in the specification.

IPC 8 full level

C07D 233/90 (2006.01); A61K 31/4164 (2006.01); A61P 29/00 (2006.01); A61P 37/00 (2006.01); C07D 401/06 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01); C07D 405/04 (2006.01); C07D 405/06 (2006.01); C07D 405/12 (2006.01); C07D 417/04 (2006.01)

CPC (source: EP)

A61P 25/04 (2017.12); A61P 29/00 (2017.12); A61P 37/00 (2017.12); A61P 43/00 (2017.12); C07D 233/90 (2013.01); C07D 401/06 (2013.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01); C07D 405/04 (2013.01); C07D 405/06 (2013.01); C07D 405/12 (2013.01); C07D 417/04 (2013.01)

Citation (search report)

See references of WO 2006087355A1

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

Designated extension state (EPC)

HR

DOCDB simple family (publication)

WO 2006087355 A1 20060824; AU 2006215567 A1 20060824; AU 2006215567 B2 20110512; BR PI0607439 A2 20100406; CA 2597896 A1 20060824; EP 1874734 A1 20080109; IL 184006 A0 20071031; JP 2008530179 A 20080807; NO 20074710 L 20070914; RU 2007134428 A 20090327; RU 2410377 C2 20110127

DOCDB simple family (application)

EP 2006060009 W 20060216; AU 2006215567 A 20060216; BR PI0607439 A 20060216; CA 2597896 A 20060216; EP 06708303 A 20060216; IL 18400607 A 20070618; JP 2007555612 A 20060216; NO 20074710 A 20070914; RU 2007134428 A 20060216