EP 1877394 A1 20080116 - PROCESS FOR THE PREPARATION OF ESCITALOPRAM OR ITS ACID ADDITION SALTS
Title (en)
PROCESS FOR THE PREPARATION OF ESCITALOPRAM OR ITS ACID ADDITION SALTS
Title (de)
VERFAHREN ZUR HERSTELLUNG VON ESCITALOPRAM ODER SEINEN SÄUREADDITIONSSALZEN
Title (fr)
PROCESSUS DE PREPARATION D'ESCITALOPRAM OU DE SES SELS D'ADDITION ACIDES
Publication
Application
Priority
- IN 2006000124 W 20060404
- IN 856DE2005 A 20050404
Abstract (en)
[origin: WO2006106531A1] The present invention relates to Formula (I), a process for the preparation of highly pure Escitalopram or its acid addition salts which comprises: a) reacting racemic diol or its ester derivative (III) with an optically active acid and at least one solvent to get enantiomerically pure diastereomer (IIIA); b) separating the enantiomerically pure diastereomer (IIIA) from its optically active acid salt by treating it with base and followed by stereo selective cyclization; c) separating the Escitalopram base.
IPC 8 full level
C07D 307/87 (2006.01)
CPC (source: EP)
C07D 307/87 (2013.01)
Citation (search report)
See references of WO 2006106531A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
DOCDB simple family (application)
IN 2006000124 W 20060404; EP 06728421 A 20060404