EP 1877548 B1 20160106 - ATTENUATED HUMAN PARAINFLUENZA VIRUS, METHODS AND USES THEREOF
Title (en)
ATTENUATED HUMAN PARAINFLUENZA VIRUS, METHODS AND USES THEREOF
Title (de)
ATTENUIERTES MENSCHLICHES PARAINFLUENZA-VIRUS, ENTSPRECHENDE VERFAHREN UND VERWENDUNGEN DAVON
Title (fr)
VIRUS PARAINFLUENZA HUMAIN ATTENUE, PROCEDES ET UTILISATIONS ASSOCIES
Publication
Application
Priority
- US 2006000666 W 20060110
- US 64331005 P 20050112
Abstract (en)
[origin: WO2007120120A2] The invention provides self replicating infectious recombinant paramyxoviruses. The recombinant paramyxovirus preferably have one or more attenuating mutations. In some embodiments, the recombinant paramyxovirus has a separate variant polynucleotide encoding a P protein and a separate monocistronic polynucleotide encoding a V protein. In some embodiments, recombinant paramyxovirus have at least one temperature sensitive mutation and one non-temperature sensitive mutation. Also provided are compositions and methods for using the recombinant paramyxoviruses as described herein.
IPC 8 full level
C12N 15/86 (2006.01); C07K 14/005 (2006.01)
CPC (source: EP US)
A61P 31/12 (2017.12 - EP); A61P 31/16 (2017.12 - EP); A61P 31/18 (2017.12 - EP); A61P 31/22 (2017.12 - EP); C07K 14/005 (2013.01 - EP US); C12N 7/00 (2013.01 - EP US); C12N 15/86 (2013.01 - EP US); A61K 2039/5254 (2013.01 - EP US); A61K 2039/5256 (2013.01 - EP US); C12N 2760/18722 (2013.01 - EP US); C12N 2760/18743 (2013.01 - EP US); C12N 2760/18761 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2007120120 A2 20071025; WO 2007120120 A3 20080626; AU 2006332044 A1 20070816; AU 2006332044 A8 20080807; CA 2605878 A1 20071025; EP 1877548 A2 20080116; EP 1877548 B1 20160106; JP 2008537683 A 20080925; US 2013052718 A1 20130228; US 9034343 B2 20150519
DOCDB simple family (application)
US 2006000666 W 20060110; AU 2006332044 A 20060110; CA 2605878 A 20060110; EP 06850427 A 20060110; JP 2008511104 A 20060110; US 200613501447 A 20060110