EP 1883395 A4 20120704 - LIPID CONSTRUCT FOR DELIVERY OF INTERFERON TO A MAMMAL
Title (en)
LIPID CONSTRUCT FOR DELIVERY OF INTERFERON TO A MAMMAL
Title (de)
LIPIDKONSTRUKT ZUR VERABREICHUNG EINES INTERFERONS AN EIN SÄUGETIER
Title (fr)
CONSTRUCTION LIPIDIQUE POUR L'ADMINISTRATION D'INTERFERON A UN MAMMIFERE
Publication
Application
Priority
- US 2006019118 W 20060516
- US 68387805 P 20050523
- US 38457506 A 20060320
Abstract (en)
[origin: WO2006127360A2] The instant invention is drawn to a hepatocyte targeted composition comprising interferon associated with a lipid construct comprising amphipathic lipid molecules and receptor binding molecule. The composition can comprise a mixture of free interferon and interferon associated with the complex. The composition can be modified to protect interferon and the complex from degradation. The invention also includes methods for the manufacture of the composition and loading interferon into the composition and recycling various components of the composition and methods of treating individuals infected with the hepatitis C and other hepatitis viruses.
IPC 8 full level
A61K 9/127 (2006.01); A61K 38/21 (2006.01)
CPC (source: EP KR)
A61K 9/127 (2013.01 - EP KR); A61K 38/21 (2013.01 - EP KR); A61K 38/212 (2013.01 - EP); A61K 38/215 (2013.01 - EP); A61K 38/217 (2013.01 - EP); A61K 47/544 (2017.07 - EP); A61P 1/16 (2017.12 - EP); A61P 31/12 (2017.12 - EP); A61P 31/14 (2017.12 - EP); A61P 31/20 (2017.12 - EP); Y02A 50/30 (2017.12 - EP)
Citation (search report)
- [Y] WO 9617596 A1 19960613 - CIBA GEIGY AG [CH], et al
- [Y] US 4603044 A 19860729 - GEHO W BLAIR [US], et al
- [XI] US 5891468 A 19990406 - MARTIN FRANCIS J [US], et al
- See references of WO 2006127360A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK YU
DOCDB simple family (publication)
WO 2006127360 A2 20061130; WO 2006127360 A3 20080110; AU 2006249479 A1 20061130; CA 2609376 A1 20061130; EP 1883395 A2 20080206; EP 1883395 A4 20120704; JP 2008542270 A 20081127; KR 20080042045 A 20080514
DOCDB simple family (application)
US 2006019118 W 20060516; AU 2006249479 A 20060516; CA 2609376 A 20060516; EP 06770516 A 20060516; JP 2008513540 A 20060516; KR 20077029917 A 20071221