Global Patent Index - EP 1888106 A4

EP 1888106 A4 20090114 - COMPOSITIONS AND METHODS FOR TREATING CONDITIONS RELATED TO EPHRIN SIGNALING WITH CUPREDOXINS

Title (en)

COMPOSITIONS AND METHODS FOR TREATING CONDITIONS RELATED TO EPHRIN SIGNALING WITH CUPREDOXINS

Title (de)

ZUSAMMENSETZUNGEN UND VERFAHREN ZUR BEHANDLUNG VON EPHRINSIGNALISIERUNG MIT CUPREDOXINEN

Title (fr)

COMPOSITIONS ET MÉTHODES DE TRAITEMENT D'ÉTATS ASSOCIÉS À LA SIGNALISATION DE L'ÉPHRINE AU MOYEN DE CUPRÉDOXINES

Publication

EP 1888106 A4 20090114 (EN)

Application

EP 06813192 A 20060519

Priority

  • US 2006019684 W 20060519
  • US 68281205 P 20050520
  • US 24410505 A 20051006
  • US 76474906 P 20060203

Abstract (en)

[origin: WO2007018671A2] The present invention relates to compositions and methods of use of cupredoxins, and variants, derivatives and structural equivalents of cupredoxins that interfere with the ephrin signaling system in mammalian cells. Specifically, the invention relates to compositions and methods that use cupredoxins, such as azurin, rusticyanin and plastocyanin, and variants, derivatives and structural equivalents thereof, to treat cancer in mammals.

IPC 8 full level

C07K 14/195 (2006.01); A61K 38/16 (2006.01); A61P 31/18 (2006.01); A61P 35/00 (2006.01); C07K 14/21 (2006.01)

CPC (source: EP KR)

A61K 39/00 (2013.01 - KR); A61K 39/02 (2013.01 - KR); A61P 1/04 (2017.12 - EP); A61P 9/00 (2017.12 - EP); A61P 13/10 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 25/28 (2017.12 - EP); A61P 31/12 (2017.12 - EP); A61P 31/18 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07K 14/195 (2013.01 - EP KR); C07K 14/21 (2013.01 - EP); A61K 38/00 (2013.01 - EP)

Citation (search report)

  • [X] WO 2005018662 A1 20050303 - UNIV ILLINOIS [US], et al
  • [X] WO 02076380 A2 20021003 - UNIV ILLINOIS [US]
  • [PX] US 2006040269 A1 20060223 - CHAKRABARTY ANANDA M [US], et al
  • [X] YAMADA TOHRU ET AL: "Bacterial redox protein azurin, tumor suppressor protein p53, and regression of cancer.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 99, no. 22, 29 October 2002 (2002-10-29), pages 14098 - 14103, XP002486971, ISSN: 0027-8424
  • [A] HIMANEN J-P ET AL: "Eph signaling: a structural view", TRENDS IN NEUROSCIENCE, ELSEVIER, AMSTERDAM, NL, vol. 26, no. 1, 1 January 2003 (2003-01-01), pages 46 - 51, XP004398871, ISSN: 0166-2236
  • [A] TOTH JOSEPH ET AL: "Crystal structure of an ephrin ectodomain", DEVELOPMENTAL CELL, vol. 1, no. 1, July 2001 (2001-07-01), pages 83 - 92, XP002505155, ISSN: 1534-5807
  • See references of WO 2007018671A2

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

DOCDB simple family (publication)

WO 2007018671 A2 20070215; WO 2007018671 A3 20071122; AU 2006277009 A1 20070215; BR PI0612424 A2 20090127; CA 2608512 A1 20070215; EP 1888106 A2 20080220; EP 1888106 A4 20090114; IL 187138 A0 20080209; JP 2008539795 A 20081120; KR 20080040631 A 20080508; MX 2007014598 A 20080207; NO 20076391 L 20080215

DOCDB simple family (application)

US 2006019684 W 20060519; AU 2006277009 A 20060519; BR PI0612424 A 20060519; CA 2608512 A 20060519; EP 06813192 A 20060519; IL 18713807 A 20071104; JP 2008512587 A 20060519; KR 20077028984 A 20071212; MX 2007014598 A 20060519; NO 20076391 A 20071211