EP 1888631 A2 20080220 - THERAPEUTIC COMPOSITION FOR USE IN THE PREVENTION AND TREATMENT OF BONE METASTASES
Title (en)
THERAPEUTIC COMPOSITION FOR USE IN THE PREVENTION AND TREATMENT OF BONE METASTASES
Title (de)
THERAPEUTSCHE ZUSAMMENSETZUNG ZUR VORBEUGUNG UND BEKÄMPFUNG VON KNOCHENMETASTASEN
Title (fr)
COMPOSITION THERAPEUTIQUE POUR PREVENIR ET COMBATTRE LES METASTASES OSSEUSES
Publication
Application
Priority
- EP 2006005191 W 20060531
- DE 102005024836 A 20050531
- DE 102006004612 A 20060201
Abstract (en)
[origin: WO2006128689A2] The invention relates to drugs on the basis of antibodies against non-cellular bone matrix proteins, especially BSP, for use in the prevention and treatment of bone metastases. According to the invention, the antibodies are induced in the patient by recombinantly expressing antigenic determinants of the bone matrix proteins in Listeria and anchoring them on the surfaces thereof. The antigenic determinants are selected according to whether they are characteristic of antigens that are expressed by the tumor cells themselves.
IPC 8 full level
C07K 14/51 (2006.01); A61K 39/00 (2006.01)
CPC (source: EP US)
A61K 39/0011 (2013.01 - EP US); A61P 37/04 (2018.01 - EP); C07K 14/51 (2013.01 - EP US); C07K 16/24 (2013.01 - EP US); C07K 16/30 (2013.01 - EP US); A61K 2039/523 (2013.01 - EP US); C07K 2317/23 (2013.01 - EP US); Y02A 50/30 (2018.01 - EP)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK YU
DOCDB simple family (publication)
WO 2006128689 A2 20061207; WO 2006128689 A3 20070823; AT E443718 T1 20091015; DE 502006004924 D1 20091105; EP 1888631 A2 20080220; EP 1888631 B1 20090923; EP 2128173 A1 20091202; EP 2128173 B1 20150121; US 2009142372 A1 20090604; US 8282943 B2 20121009
DOCDB simple family (application)
EP 2006005191 W 20060531; AT 06761953 T 20060531; DE 502006004924 T 20060531; EP 06761953 A 20060531; EP 09168763 A 20060531; US 92142106 A 20060531