EP 1888676 A2 20080220 - METHOD FOR PRODUCING A COMPOSITE MATERIAL COMPRISING ACTIVE SUBSTANCE SOLID DISPERSIONS IN A POLYMER MATRIX
Title (en)
METHOD FOR PRODUCING A COMPOSITE MATERIAL COMPRISING ACTIVE SUBSTANCE SOLID DISPERSIONS IN A POLYMER MATRIX
Title (de)
VERFAHREN ZUR HERSTELLUNG EINES WIRKSTOFFHALTIGEN VERBUNDMATERIALES
Title (fr)
PROCEDE DE FABRICATION D'UN MATÉRIAU COMPOSITE COMPRENANT UNE SUBSTANCE ACTIVE
Publication
Application
Priority
- EP 2006063110 W 20060612
- FR 0551577 A 20050610
Abstract (en)
[origin: WO2006131570A2] The invention relates to a method for producing a composite material comprising solid dispersions of an active substance in a polymer matrix consisting in introducing the polymer matrix into an extruder (1), in actuating said extruder (1) in such a way that the rheological properties of the polymer matrix are modified, in exposing a fluid to supercritical conditions and in injecting it alone or mixed with another component into the extruder (1), in particular through an injection nozzle (11), in introducing an active substance into the extruder (1), in mixing a supercritical fluid, the active substance and the polymer matrix and in de-stressing the thus obtained mixture in such a way that a microporous structure is formed therein.
IPC 8 full level
C08J 9/12 (2006.01); A61K 9/16 (2006.01); A61K 9/20 (2006.01)
CPC (source: EP)
A61K 9/146 (2013.01); A61K 9/1694 (2013.01); A61K 9/2095 (2013.01); C08J 9/122 (2013.01); C08J 2201/03 (2013.01); C08J 2203/08 (2013.01); Y02P 20/54 (2015.11)
Citation (search report)
See references of WO 2006131570A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2006131570 A2 20061214; WO 2006131570 A3 20070607; EP 1888676 A2 20080220; FR 2886938 A1 20061215; FR 2886938 B1 20080418
DOCDB simple family (application)
EP 2006063110 W 20060612; EP 06763648 A 20060612; FR 0551577 A 20050610