EP 1891231 A2 20080227 - GLYCOPEGYLATED FACTOR IX
Title (en)
GLYCOPEGYLATED FACTOR IX
Title (de)
GLYKOPEGYLIERTER FAKTOR IX
Title (fr)
FACTEUR IX GLYCOPEGYLE
Publication
Application
Priority
- US 2006020230 W 20060525
- US 68472905 P 20050525
- US 70799405 P 20050812
- US 71053505 P 20050823
Abstract (en)
[origin: WO2006127896A2] The present invention provides conjugates between Factor IX and PEG moieties. The conjugates are linked via a glycosyl linking group interposed between and covalently attached to the peptide and the modifying group. Conjugates are formed from glycosylated peptides by the action of a glycosyltransferase. The glycosyltransferase ligates a modified sugar moiety onto a glycosyl residue on the peptide. Also provided are methods for preparing the conjugates, methods for treating various disease conditions with the conjugates, and pharmaceutical formulations including the conjugates.
IPC 8 full level
C12Q 1/56 (2006.01)
CPC (source: EP US)
A61K 38/4846 (2013.01 - EP US); A61K 47/549 (2017.07 - EP US); A61K 47/60 (2017.07 - EP US); A61P 7/04 (2017.12 - EP); C12N 9/644 (2013.01 - EP US); C12Y 304/21022 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK YU
DOCDB simple family (publication)
WO 2006127896 A2 20061130; WO 2006127896 A3 20071101; EP 1891231 A2 20080227; EP 1891231 A4 20110622; EP 2975135 A1 20160120; JP 2008542285 A 20081127; JP 5216580 B2 20130619; US 2008255026 A1 20081016; US 2010081791 A1 20100401; US 2014154230 A1 20140605; US 2015125437 A1 20150507; US 2016184412 A1 20160630; US 2016361427 A1 20161215; US 2017136104 A1 20170518; US 8404809 B2 20130326
DOCDB simple family (application)
US 2006020230 W 20060525; EP 06784467 A 20060525; EP 15151467 A 20060525; JP 2008513705 A 20060525; US 201314055971 A 20131017; US 201514598478 A 20150116; US 201615005566 A 20160125; US 201615241209 A 20160819; US 201715410014 A 20170119; US 60502809 A 20091023; US 91523906 A 20060525