EP 1894570 A2 20080305 - Methods and compositions for the treatment of peripheral artery disease
Title (en)
Methods and compositions for the treatment of peripheral artery disease
Title (de)
Verfahren und Zusammensetzungen zur Behandlung von Erkrankungen der peripheren Arterie
Title (fr)
Compositions et procédés pour le traitement de maladies des artères périphériques
Publication
Application
Priority
- EP 01946663 A 20010622
- US 21350400 P 20000622
- US 26457201 P 20010126
- US 27654901 P 20010316
- US 88685601 A 20010621
Abstract (en)
Compositions and methods for treating peripheral artery disease in a patient are provided. Compositions comprise recombinant fibroblast growth factor-2. Fibroblast growth factor, such as FGF-2, is administered in therapeutically effective amounts to treat or prevent peripheral artery disease including claudication and critical limb ischemia. Pharmaceutical compositions comprising a therapeutically effective amount of FGF-2 and a pharmaceutically acceptable carrier are also provided. The methods of the invention to treat peripheral artery disease and claudication comprise administering at least a single dose of a pharmaceutical composition comprising the FGF, such as FGF-2, via intra-arterial, intravenous, or intramuscular infusion to the patient. It is recognized that increased benefits may result from multiple dosing, including intermittent dosing.
IPC 8 full level
A61K 38/18 (2006.01); A61P 9/10 (2006.01)
CPC (source: EP)
A61K 38/1825 (2013.01); A61P 9/10 (2017.12)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
DOCDB simple family (application)
EP 07024542 A 20010622