EP 1902128 A4 20090225 - APPARATUS AND METHODS FOR PREPARING TISSUE GRAFTS
Title (en)
APPARATUS AND METHODS FOR PREPARING TISSUE GRAFTS
Title (de)
VORRICHTUNG UND VERFAHREN ZUR HERSTELLUNG VON GEWEBETRANSPLANTATEN
Title (fr)
APPAREIL ET MÉTHODES DE PRÉPARATION DE GREFFES DE TISSUS
Publication
Application
Priority
- US 2006027191 W 20060712
- US 69795405 P 20050712
- US 31428105 A 20051222
Abstract (en)
[origin: WO2007009036A2] The invention provides automated apparatus and methods for manufacturing implantable tissue grafts in an operating room setting, preferably utilizing autologous adipose tissue cells for preparing vascular grafts. The automated apparatus includes media and tissue dissociating chemical reservoirs, filters, a cell separator and a perfusion flow loop through a biochamber which supports a graft substrate. The present invention further provides methods for using the tissue grafts and cell samples prepared by the devices described herein in a multitude of therapies including revascularization, regeneration and reconstruction of tissues and organs, as well as treatment and prevention of diseases. The invention also provides methods biochamber configurations for applying a sustained low pressure gradient across a permeable scaffold material using a media containing cells to be deposited on the scaffold for the production of tissue grafts, including, but not limited to, vascular grafts.
IPC 8 full level
C12M 3/00 (2006.01); C12N 5/071 (2010.01)
CPC (source: EP)
C12M 21/08 (2013.01); C12M 25/14 (2013.01); C12M 29/10 (2013.01); C12M 45/06 (2013.01); C12N 5/0697 (2013.01)
Citation (search report)
- [Y] US 6416995 B1 20020709 - WOLFINBARGER LLOYD [US]
- [X] US 5792603 A 19980811 - DUNKELMAN NOUSHIN [US], et al
- [XY] WO 9501419 A1 19950112 - BAXTER INT [US]
- [A] US 4028190 A 19770607 - MCALEER WILLIAM J, et al
- See references of WO 2007009036A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2007009036 A2 20070118; WO 2007009036 A3 20070531; WO 2007009036 A9 20070315; AU 2006268129 A1 20070118; CA 2615208 A1 20070118; EP 1902128 A2 20080326; EP 1902128 A4 20090225; JP 2009501562 A 20090122
DOCDB simple family (application)
US 2006027191 W 20060712; AU 2006268129 A 20060712; CA 2615208 A 20060712; EP 06787137 A 20060712; JP 2008521605 A 20060712