EP 1907372 A1 20080409 - SUBSTITUTED CYCLOHEXYL DERIVATIVES AS NK-3 RECEPTOR ANTAGONISTS
Title (en)
SUBSTITUTED CYCLOHEXYL DERIVATIVES AS NK-3 RECEPTOR ANTAGONISTS
Title (de)
SUBSTITUIERTE CYCLOHEXYLDERIVATE ALS NK-3-REZEPTORANTAGONISTEN
Title (fr)
DÉRIVÉS DE CYCLOHEXYLE SUBSTITUÉ COMME ANTAGONISTES DES RÉCEPTEURS NK-3
Publication
Application
Priority
- GB 2006050184 W 20060704
- GB 0513747 A 20050706
Abstract (en)
[origin: WO2007003965A1] The present invention relates to the compounds of formula (I): wherein A,B, n, X, Y, Z, R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP>, R<SUP>5</SUP>, R<SUP>6</SUP>, R<SUP>7</SUP> and R<SUP>8</SUP> are defined herein, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising them and their use in treating diseases mediated by neurokinin-3 (NK-3) receptors. These compounds can thus be used in methods of treatment to suppress and treat such disorders.
IPC 8 full level
A61K 31/10 (2006.01); A61K 31/445 (2006.01); A61P 25/18 (2006.01); A61P 25/22 (2006.01); A61P 25/24 (2006.01); C07C 317/14 (2006.01); C07C 317/30 (2006.01); C07D 207/14 (2006.01); C07D 211/34 (2006.01); C07D 213/38 (2006.01); C07D 265/30 (2006.01); C07D 401/04 (2006.01); C07D 403/04 (2006.01); C07D 413/04 (2006.01); C07D 417/04 (2006.01); C07D 471/04 (2006.01); C07D 471/10 (2006.01)
CPC (source: EP)
A61P 1/00 (2017.12); A61P 1/04 (2017.12); A61P 1/08 (2017.12); A61P 3/10 (2017.12); A61P 9/10 (2017.12); A61P 9/12 (2017.12); A61P 11/00 (2017.12); A61P 11/06 (2017.12); A61P 11/16 (2017.12); A61P 13/02 (2017.12); A61P 13/12 (2017.12); A61P 15/10 (2017.12); A61P 15/12 (2017.12); A61P 21/00 (2017.12); A61P 21/02 (2017.12); A61P 25/04 (2017.12); A61P 25/08 (2017.12); A61P 25/14 (2017.12); A61P 25/16 (2017.12); A61P 25/18 (2017.12); A61P 25/20 (2017.12); A61P 25/22 (2017.12); A61P 25/24 (2017.12); A61P 25/28 (2017.12); A61P 25/32 (2017.12); A61P 43/00 (2017.12); C07C 317/30 (2013.01); C07D 207/14 (2013.01); C07D 211/34 (2013.01); C07D 213/38 (2013.01); C07D 265/30 (2013.01); C07D 401/04 (2013.01); C07D 403/04 (2013.01); C07D 413/04 (2013.01); C07D 417/04 (2013.01); C07D 471/04 (2013.01); C07D 471/10 (2013.01); C07C 2601/14 (2017.04)
Citation (search report)
See references of WO 2007003965A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2007003965 A1 20070111; AU 2006264652 A1 20070111; CA 2611867 A1 20070111; EP 1907372 A1 20080409; GB 0513747 D0 20050810; JP 2008544978 A 20081211
DOCDB simple family (application)
GB 2006050184 W 20060704; AU 2006264652 A 20060704; CA 2611867 A 20060704; EP 06744364 A 20060704; GB 0513747 A 20050706; JP 2008518986 A 20060704