EP 1917015 A1 20080507 - NOVEL 4-AMINO-THIENO[3,2-C]PYRIDINE-7-CARBOXYLIC ACID AMIDES
Title (en)
NOVEL 4-AMINO-THIENO[3,2-C]PYRIDINE-7-CARBOXYLIC ACID AMIDES
Title (de)
NEUE 4-AMINO-THIENO[3,2-C]PYRIDIN-7-CARBONSÄUREAMIDE
Title (fr)
NOUVEAUX AMIDES DE L'ACIDE 4-AMINO-THIÉNO[3,2-C]PYRIDINE-7-CARBOXYLIQUE
Publication
Application
Priority
EP 2005054022 W 20050816
Abstract (en)
[origin: WO2007019884A1] The present invention relates to novel 4-amino-thieno[3,2-c]pyridine-7-carboxylic acid amides of formula (I), and their pharmaceutically acceptable salts and esters which compounds of formula (I) are selective inhibitors of KDR and/or FGFR kinases. These compounds and their pharmaceutically acceptable salts are anti-proliferative agents useful in the treatment or control of solid tumors, in particular solid tumors of the breast, colon, lung and prostate. Also disclosed are pharmaceutical compositions or medicaments containing these compounds, processes for making them and methods of treating cancer using these compounds.
IPC 8 full level
A61K 31/4365 (2006.01); A61P 35/00 (2006.01); C07D 495/04 (2006.01)
CPC (source: EP KR)
A61P 35/00 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 495/04 (2013.01 - EP KR)
Citation (search report)
See references of WO 2007019884A1
Citation (examination)
US 2005020619 A1 20050127 - BETSCHMANN PATRICK [US], et al
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2007019884 A1 20070222; AU 2005335661 A1 20070222; BR PI0520482 A2 20090512; CA 2619459 A1 20070222; EP 1917015 A1 20080507; IL 189181 A0 20080605; JP 2009504692 A 20090205; KR 100995790 B1 20101122; KR 20080027945 A 20080328; MX 2008002060 A 20080416
DOCDB simple family (application)
EP 2005054022 W 20050816; AU 2005335661 A 20050816; BR PI0520482 A 20050816; CA 2619459 A 20050816; EP 05792209 A 20050816; IL 18918108 A 20080203; JP 2008526383 A 20050816; KR 20087003603 A 20050816; MX 2008002060 A 20050816