EP 1928905 B1 20150415 - BINDING DOMAINS OF PROTEINS OF THE REPULSIVE GUIDANCE MOLECULE (RGM) PROTEIN FAMILY AND FUNCTIONAL FRAGMENTS THEREOF, AND THEIR USE
Title (en)
BINDING DOMAINS OF PROTEINS OF THE REPULSIVE GUIDANCE MOLECULE (RGM) PROTEIN FAMILY AND FUNCTIONAL FRAGMENTS THEREOF, AND THEIR USE
Title (de)
BINDUNGSDOMÄNEN VON PROTEINEN DER REPULSIVE GUIDANCE MOLECULE (RGM) PROTEINFAMILIE UND FUNKTIONALE FRAGMENTE DAVON SOWIE DEREN VERWENDUNG
Title (fr)
DOMAINES DE LIAISON DE PROTEINES DE LA FAMILLE PROTEINIQUE DES MOLECULES DE GUIDAGE REPULSIF (RGM), FRAGMENTS FONCTIONNELS DE CES DOMAINES ET LEUR UTILISATION
Publication
Application
Priority
- EP 2006009497 W 20060929
- EP 05021451 A 20050930
- US 72256505 P 20051001
- EP 06805972 A 20060929
Abstract (en)
[origin: WO2007039256A2] The invention concerns the identification and use of neogenin receptor-binding domains of members of the repulsive guidance molecule (RGM) protein family as well as polypeptide fragments derived therefrom. The inventive domains, i.e. peptide fragments are suited as agents for the active or passive immunization of individuals as well as diagnostic and therapeutic agents for use with diseases or pathological conditions in whose origin or progression, a member of the RGM family and a cellular receptor assigned to this molecule are involved. The invention also concerns monoclonal and polyclonal antibodies directed against the inventive binding domains and against the polypeptides derived therefrom, and to method for producing the inventive domains, polypeptides and antibodies.
IPC 8 full level
A61K 39/395 (2006.01); A61P 25/00 (2006.01); C07K 14/475 (2006.01); C07K 14/71 (2006.01); C07K 16/28 (2006.01)
CPC (source: EP US)
A61P 3/00 (2017.12 - EP); A61P 19/08 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 25/04 (2017.12 - EP); A61P 25/28 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 37/02 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07K 14/705 (2013.01 - EP US); C07K 16/28 (2013.01 - EP US); A61K 38/00 (2013.01 - EP US); C07K 2317/34 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
HR
DOCDB simple family (publication)
WO 2007039256 A2 20070412; WO 2007039256 A3 20070705; CA 2624562 A1 20070412; CN 101277974 A 20081001; EP 1928905 A2 20080611; EP 1928905 B1 20150415; ES 2542501 T3 20150806; JP 2009510002 A 20090312; US 2009297527 A1 20091203; US 8906864 B2 20141209
DOCDB simple family (application)
EP 2006009497 W 20060929; CA 2624562 A 20060929; CN 200680036346 A 20060929; EP 06805972 A 20060929; ES 06805972 T 20060929; JP 2008532684 A 20060929; US 99272006 A 20060929