Global Patent Index - EP 1929291 A4

EP 1929291 A4 20101222 - ESTRIOL THERAPY FOR AUTOIMMUNE AND NEURODEGENERATAIVE DISEASES AND DISORDERS

Title (en)

ESTRIOL THERAPY FOR AUTOIMMUNE AND NEURODEGENERATAIVE DISEASES AND DISORDERS

Title (de)

ÖSTRIOLTHERAPIE FÜR AUTOIMMUN- UND NEURODEGENERATIVE KRANKHEITEN UND ERKRANKUNGEN

Title (fr)

THERAPIE PAR ESTRIOL POUR MALADIE DES TROUBLES AUTO-IMMUNS ET NEURODEGENERATIFS

Publication

EP 1929291 A4 20101222 (EN)

Application

EP 06815626 A 20060926

Priority

  • US 2006037752 W 20060926
  • US 72097205 P 20050926
  • US 83352706 P 20060726

Abstract (en)

[origin: WO2007038636A2] The present invention discloses administering steroid hormones to mammals to treat autoimmune related diseases, neurodegenerative diseases or disorders, such as Alzheimer's disease, Parkinson's Disease, multiple sclerosis, stroke, ALS Pick's disease, prion disease and Huntington's disease. Most preferably the invention uses estrogens, estranges, estriol or estrogen receptor active agents to prevent or ameliorate clinical symptoms of the diseases and disorders.

IPC 8 full level

G01N 33/00 (2006.01); A61K 31/565 (2006.01); A61K 31/566 (2006.01); A61K 31/568 (2006.01); A61K 45/06 (2006.01)

CPC (source: EP)

A61K 31/565 (2013.01); A61K 31/566 (2013.01); A61K 31/568 (2013.01); A61K 31/57 (2013.01); A61K 31/785 (2013.01); A61K 45/06 (2013.01); A61P 5/24 (2017.12); A61P 5/30 (2017.12); A61P 5/34 (2017.12); A61P 5/40 (2017.12); A61P 9/00 (2017.12); A61P 15/00 (2017.12); A61P 25/00 (2017.12); A61P 25/02 (2017.12); A61P 25/14 (2017.12); A61P 25/16 (2017.12); A61P 25/28 (2017.12); A61P 35/00 (2017.12)

Citation (search report)

  • [X] US 5554601 A 19960910 - SIMPKINS JAMES W [US], et al
  • [X] US 2001016325 A1 20010823 - MOBLEY WILLIAM C [US], et al
  • [X] PERRELLA, JOEL ET AL: "Protection of cortical cells by equine estrogens against glutamate-induced excitotoxicity is mediated through a calcium independent mechanism", BMC NEUROSCIENCE, vol. 6, 34, 10 May 2005 (2005-05-10), pages 17PP, XP002605592, ISSN: 1471-2202
  • [X] KUMAR D M ET AL: "Role of nonfeminizing estrogen analogues in neuroprotection of rat retinal ganglion cells against glutamate-induced cytotoxicity", FREE RADICAL BIOLOGY AND MEDICINE, vol. 38, no. 9, 1 May 2005 (2005-05-01), ELSEVIER SCIENCE, US, pages 1152 - 1163, XP025352119, ISSN: 0891-5849, [retrieved on 20050501]
  • [X] BIEWENGA E ET AL: "Estradiol and raloxifene protect cultured SN4741 neurons against oxidative stress", NEUROSCIENCE LETTERS, vol. 373, no. 3, 20 January 2005 (2005-01-20), LIMERICK, IE, pages 179 - 183, XP004690113, ISSN: 0304-3940, DOI: 10.1016/J.NEULET.2004.09.067
  • [X] OFFNER, HALINA: "Neuroimmunoprotective effects of estrogen and derivatives in experimental autoimmune encephalomyelitis: Therapeutic implications for multiple sclerosis", JOURNAL OF NEUROSCIENCE RESEARCH, vol. 78, no. 5, 28 October 2004 (2004-10-28), pages 603 - 624, XP002605593, ISSN: 0360-4012
  • [X] SAMANTHA S SOLDAN ET AL: "Immune modulation in multiple sclerosis patients treated with the pregnancy hormone estriol", JOURNAL OF IMMUNOLOGY, vol. 171, no. 11, 1 December 2003 (2003-12-01), AMERICAN ASSOCIATION OF IMMUNOLOGISTS, US, pages 6267 - 6268, XP008126547, ISSN: 0022-1767
  • [X] WEN, YI ET AL: "Transient Cerebral Ischemia Induces Aberrant Neuronal Cell Cycle Re-entry and Alzheimer 's Disease-like Tauopathy in Female Rats", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 279, no. 21, 24 February 2004 (2004-02-24), pages 22684 - 22692, XP002605887, ISSN: 0021-9258
  • See references of WO 2007038636A2

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

DOCDB simple family (publication)

WO 2007038636 A2 20070405; WO 2007038636 A3 20071227; AU 2006294662 A1 20070405; CA 2623839 A1 20070405; CA 2623839 C 20131217; EP 1929291 A2 20080611; EP 1929291 A4 20101222; EP 2698167 A2 20140219; EP 2698167 A3 20140305; EP 3045177 A1 20160720; JP 2009510084 A 20090312

DOCDB simple family (application)

US 2006037752 W 20060926; AU 2006294662 A 20060926; CA 2623839 A 20060926; EP 06815626 A 20060926; EP 13005320 A 20060926; EP 16000349 A 20060926; JP 2008533586 A 20060926