EP 1931387 A4 20120711 - BIODEGRADABLE MICROPARTICLE PHARMACEUTICAL FORMULATIONS EXHIBITING IMPROVED RELEASE RATES
Title (en)
BIODEGRADABLE MICROPARTICLE PHARMACEUTICAL FORMULATIONS EXHIBITING IMPROVED RELEASE RATES
Title (de)
BIOLOGISCH ABBAUBARE MIKROTEILCHENFÖRMIGE PHARMAZEUTISCHE FORMULIERUNGEN MIT VERBESSERTEN FREISETZUNGSRATEN
Title (fr)
FORMULATIONS PHARMACEUTIQUES DE MICROPARTICULES BIODEGRADABLES PRESENTANT DES TAUX DE LIBERATION AMELIORES
Publication
Application
Priority
- US 2006034722 W 20060906
- US 22043105 A 20050907
- US 22044505 A 20050907
- US 22080705 A 20050907
- US 22133705 A 20050907
- US 22043005 A 20050907
Abstract (en)
[origin: WO2007030545A2] This invention is directed to an apparatus and method for producing microparticles comprising pharmacologically active agents and biodegradable polymers. The apparatus (100) includes a spinning disk (105) containing a reservoir (708) in the center thereof and a flat inclined surface. The apparatus optionally includes serrations (712) and/or a flat surface beneath the periphery of the disk that is parallel to the rotational axis of the disk. The invention is also directed to a method for producing microparticles containing pharmacologically active agents, using the spinning disk apparatus. Formulations containing ophthalmically active agents are provided. Formulations exhibiting zero order release rates are also described.
IPC 8 full level
A61K 9/00 (2006.01); A61K 9/16 (2006.01); A61K 9/52 (2006.01); A61K 47/00 (2006.01); A61K 47/30 (2006.01); A61K 47/32 (2006.01)
CPC (source: EP KR)
A61K 9/0048 (2013.01 - EP); A61K 9/16 (2013.01 - KR); A61K 9/50 (2013.01 - KR); A61K 9/5031 (2013.01 - EP); A61K 47/30 (2013.01 - KR); A61K 9/1647 (2013.01 - EP)
Citation (search report)
- [XI] WO 2005018794 A1 20050303 - DANISCO [DK], et al
- [XI] WO 2004041251 A1 20040521 - OCEAN NUTRITION CANADA LTD [CA], et al
- [A] US 5665428 A 19970909 - CHA YOUNSIK [US], et al
- [A] US 4256677 A 19810317 - LEE LAWRENCE L
- See references of WO 2007030545A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2007030545 A2 20070315; WO 2007030545 A3 20071108; AU 2006287499 A1 20070315; BR PI0615563 A2 20110524; CA 2621395 A1 20070315; EP 1931387 A2 20080618; EP 1931387 A4 20120711; JP 2009507845 A 20090226; KR 20080059175 A 20080626
DOCDB simple family (application)
US 2006034722 W 20060906; AU 2006287499 A 20060906; BR PI0615563 A 20060906; CA 2621395 A 20060906; EP 06803043 A 20060906; JP 2008530171 A 20060906; KR 20087008002 A 20080402