EP 1932920 A1 20080618 - METHOD FOR SCREENING OF SUBSTANCE EFFECTIVE ON DISEASE USING GPR120 AND PHOSPHOLIPASE
Title (en)
METHOD FOR SCREENING OF SUBSTANCE EFFECTIVE ON DISEASE USING GPR120 AND PHOSPHOLIPASE
Title (de)
SCREENING-VERFAHREN FÜR EINE GEGEN KRANKHEIT WIRKSAME SUBSTANZ UNTER VERWENDUNG VON GPR120 UND PHOSPHOLIPASE
Title (fr)
METHODE POUR DETECTER UNE SUBSTANCE EFFICACE CONTRE UNE MALADIE AU MOYEN DE GPR120 ET DE PHOSPHOLIPASE
Publication
Application
Priority
- JP 2006317331 W 20060901
- JP 2005254643 A 20050902
Abstract (en)
The present invention provides a screening method for determining whether a substance of interest is a substance which alters GPR120 mediated cell stimulating activities, comprising using a substance of interest, a biomembrane containing GPR120, or cells containing said biomembrane, and phospholipase or salts thereof. According to a screening method of the present invention, the method can screen substances such as CCK and GLP-1 which are involved in the secretion of hormones in gastrointestinal tracts.
IPC 8 full level
C12Q 1/44 (2006.01); C07K 14/705 (2006.01); C12N 9/16 (2006.01); C12N 15/09 (2006.01); C12Q 1/02 (2006.01); C12Q 1/34 (2006.01); C12Q 1/68 (2006.01); G01N 33/15 (2006.01); G01N 33/50 (2006.01)
CPC (source: EP US)
G01N 33/566 (2013.01 - EP US); G01N 2333/595 (2013.01 - EP US); G01N 2333/918 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK RS
DOCDB simple family (publication)
EP 1932920 A1 20080618; EP 1932920 A4 20090408; JP 4932724 B2 20120516; JP WO2007026874 A1 20090312; US 2011183318 A1 20110728; US 8399204 B2 20130319; WO 2007026874 A1 20070308
DOCDB simple family (application)
EP 06797273 A 20060901; JP 2006317331 W 20060901; JP 2007533357 A 20060901; US 99144106 A 20060901