EP 1937242 A4 20110615 - METHODS AND COMPOSITIONS FOR THE TREATMENT OF NEUROPSYCHIATRIC AND ADDICTIVE DISORDERS
Title (en)
METHODS AND COMPOSITIONS FOR THE TREATMENT OF NEUROPSYCHIATRIC AND ADDICTIVE DISORDERS
Title (de)
VERFAHREN UND ZUSAMMENSETZUNGEN ZUR BEHANDLUNG NEUROPSYCHIATRISCHER ERKRANKUNGEN UND SUCHTKRANKHEITEN
Title (fr)
PROCEDES ET COMPOSITIONS POUR TRAITER DES TROUBLES NEUROPSYCHIATRIQUES ET DES TROUBLES LIES A LA DEPENDANCE
Publication
Application
Priority
- US 2006040598 W 20061017
- US 72756405 P 20051017
- US 72731805 P 20051017
- US 25172405 A 20051017
- US 54927406 A 20061013
Abstract (en)
[origin: WO2007047698A2] The present invention relates to methods and compositions for treating neuropathic pain and neuropsychiatric disorders by administering agents that are effective in reducing the effective amount, inactivating, and/or inhibiting the activity of a Na<SUP>+</SUP>-K<SUP>+</SUP>-2Cl<SUP>-</SUP> (NKCC) cotransporter. In certain embodiments, the Na<SUP>+</SUP>-K<SUP>+</SUP>-2Cl<SUP>-</SUP> co-transporter is NKCC1.
IPC 8 full level
A61K 31/341 (2006.01); A61K 31/381 (2006.01); A61K 31/41 (2006.01); A61P 25/08 (2006.01); C07C 311/00 (2006.01); C07D 207/06 (2006.01); C07D 213/34 (2006.01); C07D 257/04 (2006.01); C07D 307/52 (2006.01); C07D 333/10 (2006.01)
CPC (source: EP)
A61K 31/18 (2013.01); A61K 31/34 (2013.01); A61K 31/40 (2013.01); A61K 31/41 (2013.01); A61K 31/44 (2013.01); A61K 31/549 (2013.01); A61P 25/08 (2017.12)
Citation (search report)
- [X] US 2002082252 A1 20020627 - HOCHMAN DARYL W [US]
- [E] WO 2007047447 A2 20070426 - NEUROTHERAPEUTICS PHARMA LLC [US], et al
- [XD] M. A. COLLINS ET AL.: "Brain damage due to episodic alcohol exposure in vivo and in vitro: furosemide neuroprotection implicates edema-based mechanism", THE FASEB JOURNAL, vol. 12, 1998, pages 221 - 230, XP002634773
- See references of WO 2007047698A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK RS
DOCDB simple family (publication)
WO 2007047698 A2 20070426; WO 2007047698 A3 20070705; EP 1937242 A2 20080702; EP 1937242 A4 20110615
DOCDB simple family (application)
US 2006040598 W 20061017; EP 06826134 A 20061017