EP 1940449 A2 20080709 - WOUND-HEALING PHARMACEUTICAL COMPOSITIONS COMPRISING AT LEAST ONE SOLUBLE DEXTRAN AND AT LEAST ONE PLATELET-DERIVED GROWTH FACTOR
Title (en)
WOUND-HEALING PHARMACEUTICAL COMPOSITIONS COMPRISING AT LEAST ONE SOLUBLE DEXTRAN AND AT LEAST ONE PLATELET-DERIVED GROWTH FACTOR
Title (de)
PHARMAZEUTISCHE WUNDHEILUNGSZUSAMMENSETZUNGEN MIT MINDESTENS EINEM LÖSLICHEN DEXTRAN UND MINDESTENS EINEM PDGF (PLATELET-DERIVED GROWTH FACTOR)
Title (fr)
COMPOSITIONS PHARMACEUTIQUES A ACTIVITE CICATRISANTE COMPRENANT AU MOINS UN DERIVE DE DEXTRANE SOLUBLE ET AU MOINS UN FACTEUR DE CROISSANCE DERIVE DES PLAQUETTES
Publication
Application
Priority
- IB 2006002667 W 20060926
- FR 0509803 A 20050926
Abstract (en)
[origin: WO2007034320A2] The invention concerns novel platelet-derived growth factor (PDGF) complexes associated with amphiphilic polymers for enhancing the physical and chemical in vitro and in vivo stability of the therapeutic protein for pharmaceutical applications. The invention also concerns a method for preparing the PDGF-amphiphilic polymer complex characterized in that it consists in preparing said polymer/PDGF-BB complex in an aqueous medium and in the absence of organic solvent likely to cause denaturation of the protein and the use of said PDGF-amphiphilic polymer complex for preparing a therapeutic wound-healing composition for topically treating ulcers.
IPC 8 full level
A61K 38/18 (2006.01); A61K 47/36 (2006.01); A61P 17/02 (2006.01)
CPC (source: EP KR US)
A61K 38/18 (2013.01 - KR); A61K 38/1858 (2013.01 - EP US); A61K 47/30 (2013.01 - KR); A61K 47/36 (2013.01 - EP KR US); A61P 1/04 (2017.12 - EP); A61P 3/10 (2017.12 - EP); A61P 17/02 (2017.12 - EP)
Citation (search report)
See references of WO 2007034321A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
FR 2891149 A1 20070330; FR 2891149 B1 20071130; AU 2006293613 A1 20070329; AU 2006293613 B2 20120517; BR PI0616439 A2 20110621; CA 2623529 A1 20070329; CA 2623529 C 20131224; CN 101316607 A 20081203; CN 101631804 A 20100120; CN 101631804 B 20121128; CN 103203023 A 20130717; CN 103203023 B 20160601; DK 1940448 T3 20130603; EP 1940448 A2 20080709; EP 1940448 B1 20130306; EP 1940449 A2 20080709; ES 2406229 T3 20130606; IL 190400 A 20150831; JP 2009509952 A 20090312; JP 5438968 B2 20140312; KR 101506593 B1 20150330; KR 20080080278 A 20080903; PL 1940448 T3 20130830; PT 1940448 E 20130415; RU 2008116585 A 20091110; RU 2424824 C2 20110727; US 2007254828 A1 20071101; US 2009221805 A1 20090903; US 2011301086 A1 20111208; US 8241620 B2 20120814; WO 2007034320 A2 20070329; WO 2007034320 A3 20071004; WO 2007034321 A2 20070329; WO 2007034321 A3 20071004; ZA 200803500 B 20120926; ZA 200902008 B 20100929
DOCDB simple family (application)
FR 0509803 A 20050926; AU 2006293613 A 20060926; BR PI0616439 A 20060926; CA 2623529 A 20060926; CN 200680044233 A 20060926; CN 200780035666 A 20070926; CN 201310120297 A 20060926; DK 06808894 T 20060926; EP 06808894 A 20060926; EP 06808895 A 20060926; ES 06808894 T 20060926; IB 2006002666 W 20060926; IB 2006002667 W 20060926; IL 19040008 A 20080324; JP 2008531815 A 20060926; KR 20087009706 A 20060926; PL 06808894 T 20060926; PT 06808894 T 20060926; RU 2008116585 A 20060926; US 201113067299 A 20110523; US 52667806 A 20060926; US 52673506 A 20060926; ZA 200803500 A 20080421; ZA 200902008 A 20090320